(S)-3-(tert-butyldimethylsilyloxy)-1-cyclohexylpropan-1-ol

Base Information

• Chemical Name: (S)-3-(tert-butyldimethylsilyloxy)-1-cyclohexylpropan-1-ol
• CAS No.: 1196532-11-2
• Molecular Formula: C₁₅H₃₂O₂Si
• Molecular Weight: 272.503
• Mol file: 1196532-11-2.mol

Synonyms:(S)-3-(tert-butyldimethylsilyloxy)-1-cyclohexylpropan-1-ol

Chemical Property of (S)-3-(tert-butyldimethylsilyloxy)-1-cyclohexylpropan-1-ol

Chemical Property:

Purity/Quality:

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Technology Process of (S)-3-(tert-butyldimethylsilyloxy)-1-cyclohexylpropan-1-ol

There total 1 articles about (S)-3-(tert-butyldimethylsilyloxy)-1-cyclohexylpropan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(S)-1-cyclohexyl-1,3-propanediol (172376-40-8) + tert-butyldimethylsilyl chloride (18162-48-6) → (S)-3-(tert-butyldimethylsilyloxy)-1-cyclohexylpropan-1-ol (1196532-11-2)

Guidance literature:

With 1H-imidazole; In dichloromethane; for 1.5h; Inert atmosphere;

DOI:10.1021/ol9022062

Reference yield: 62.0%

(3S,4R)-3-(tert-butyldimethylsilyloxy)-4-methylhex-5-en-1-ol (1196532-16-7) + (S)-3-(tert-butyldimethylsilyloxy)-1-cyclohexylpropan-1-ol (1196532-11-2) → C28H56O4Si2 (1196532-17-8)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 18h; Inert atmosphere;

DOI:10.1021/ol9022062

upstream raw materials:

(S)-1-cyclohexyl-1,3-propanediol

tert-butyldimethylsilyl chloride

Downstream raw materials:

C₂₈H₅₆O₄Si₂