2-guanidino-5-<2-(trifluoromethyl)phenyl>-1,3,4-thiadiazole hydrochloride

Base Information

Chemical Name:2-guanidino-5-<2-(trifluoromethyl)phenyl>-1,3,4-thiadiazole hydrochloride
CAS No.:107114-83-0
Molecular Formula:C₁₀H₈F₃N₅S*ClH
Molecular Weight:323.729
Hs Code.:

Synonyms:2-guanidino-5-<2-(trifluoromethyl)phenyl>-1,3,4-thiadiazole hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-guanidino-5-<2-(trifluoromethyl)phenyl>-1,3,4-thiadiazole hydrochloride

Chemical Property:

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Technology Process of 2-guanidino-5-<2-(trifluoromethyl)phenyl>-1,3,4-thiadiazole hydrochloride

There total 2 articles about 2-guanidino-5-<2-(trifluoromethyl)phenyl>-1,3,4-thiadiazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethereal HCl: ethereal HCl

: 50-01-1
guanidine hydrochloride

: 107115-00-4
2-chloro-5-[2-(trifluoromethyl)phenyl]-1,3,4-thiadiazole

: 107114-83-0
2-guanidino-5-<2-(trifluoromethyl)phenyl>-1,3,4-thiadiazole hydrochloride

Guidance literature:: With sodium; In ethanol; water; tert-butyl alcohol;

Reference yield:

: 593-85-1,90332-86-8,3425-08-9
diguanidine carbonate

: 107115-00-4
2-chloro-5-[2-(trifluoromethyl)phenyl]-1,3,4-thiadiazole

: 107114-83-0
N-[5-(2-Trifluoromethyl-phenyl)-[1,3,4]thiadiazol-2-yl]-guanidine; hydrochloride

Guidance literature:: With hydrogenchloride; sodium hydroxide; Yield given. Multistep reaction; 1.) methanol, room temperature, 2.) dioxane, reflux;
DOI:10.1021/jm00400a004