11β-(4-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)phenyl)estra-1,3,5(10)-triene-3,17β-diol

Base Information

Chemical Name:11β-(4-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)phenyl)estra-1,3,5(10)-triene-3,17β-diol
CAS No.:1236152-92-3
Molecular Formula:C₃₀H₃₉N₃O₅
Molecular Weight:521.657
Hs Code.:

Synonyms:11β-(4-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)phenyl)estra-1,3,5(10)-triene-3,17β-diol

Suppliers and Price of 11β-(4-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)phenyl)estra-1,3,5(10)-triene-3,17β-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 11β-(4-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)phenyl)estra-1,3,5(10)-triene-3,17β-diol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 11β-(4-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)phenyl)estra-1,3,5(10)-triene-3,17β-diol

There total 11 articles about 11β-(4-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)phenyl)estra-1,3,5(10)-triene-3,17β-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1236152-98-9
(8S,9R,11S,13S,14S)-11-(4-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)phenyl)-7,8,9,11,12,13,15,16-octahydro-3-hydroxy-13-methyl-6hcyclopenta[a]phenanthren-17(14H)-one

: 1236152-92-3
11β-(4-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)phenyl)estra-1,3,5(10)-triene-3,17β-diol

Guidance literature:: With methanol; sodium tetrahydroborate; at 0 - 5 ℃; for 2.5h;
DOI:10.1016/j.bmc.2012.04.041

Reference yield:

: 19249-03-7
triethylene glycol di-(p-toluenesulfonate)

: 1236152-92-3
11β-(4-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)phenyl)estra-1,3,5(10)-triene-3,17β-diol

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium azide / ethanol / 2 h / Reflux

2.1: potassium carbonate / acetonitrile / 0.08 h

2.2: 10 h / 80 °C

3.1: potassium hydroxide / methanol; hexane

4.1: methanol; sodium tetrahydroborate / 2.5 h / 0 - 5 °C

With methanol; sodium tetrahydroborate; sodium azide; potassium carbonate; potassium hydroxide; In methanol; ethanol; hexane; acetonitrile; 2.2: Williamson synthesis;
DOI:10.1016/j.bmc.2012.04.041

Reference yield:

: 55180-24-0,130273-69-7
3,3,17,17-di(ethylenedioxy)-5,10-epoxy-estr-9⁽¹¹⁾-ene

: 1236152-92-3
11β-(4-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)phenyl)estra-1,3,5(10)-triene-3,17β-diol

Guidance literature:: Multi-step reaction with 4 steps

1.1: copper(l) chloride / tetrahydrofuran / Inert atmosphere

1.2: 1 h / 20 °C / Inert atmosphere

2.1: potassium carbonate / acetonitrile / 0.08 h

2.2: 10 h / 80 °C

3.1: potassium hydroxide / methanol; hexane

4.1: methanol; sodium tetrahydroborate / 2.5 h / 0 - 5 °C

With methanol; sodium tetrahydroborate; potassium carbonate; copper(l) chloride; potassium hydroxide; In tetrahydrofuran; methanol; hexane; acetonitrile; 2.2: Williamson synthesis;
DOI:10.1016/j.bmc.2012.04.041