4-((4-(3,4-bimethoxybenzyl)-2-azido-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine

Base Information

Chemical Name:4-((4-(3,4-bimethoxybenzyl)-2-azido-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine
CAS No.:1620893-68-6
Molecular Formula:C₂₄H₃₀N₆O₂
Molecular Weight:434.541
Hs Code.:

Synonyms:4-((4-(3,4-bimethoxybenzyl)-2-azido-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine

Suppliers and Price of 4-((4-(3,4-bimethoxybenzyl)-2-azido-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-((4-(3,4-bimethoxybenzyl)-2-azido-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-((4-(3,4-bimethoxybenzyl)-2-azido-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine

There total 6 articles about 4-((4-(3,4-bimethoxybenzyl)-2-azido-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 1620893-66-4
4-((4-(3,4-dimethoxybenzyl)-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine

: 1620893-68-6
4-((4-(3,4-bimethoxybenzyl)-2-azido-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine

Guidance literature:: 4-((4-(3,4-dimethoxybenzyl)-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 25 ℃; for 0.5h;

With 4-toluenesulfonyl azide; In tetrahydrofuran; hexane; at -78 - 25 ℃; for 1h;
DOI:10.1016/j.ejmech.2014.06.016

Reference yield:

: 120-21-8
4-Diethylaminobenzaldehyde

: 1620893-68-6
4-((4-(3,4-bimethoxybenzyl)-2-azido-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine

Guidance literature:: Multi-step reaction with 6 steps

1.1: ethylmagnesium bromide / tetrahydrofuran / 0.5 h / 25 °C / Inert atmosphere

1.2: 24 h / 25 °C / Inert atmosphere

2.1: triethylsilane; boron trifluoride diethyl etherate / tetrahydrofuran / 24 h / 0 - 60 °C / Inert atmosphere

3.1: ethylmagnesium bromide / tetrahydrofuran / 0.5 h / 25 °C / Inert atmosphere

3.2: 12 h / 25 °C / Inert atmosphere

4.1: tetrahydrofuran / 12 h / 25 °C / Inert atmosphere

5.1: acetic acid; hydrogen; palladium 10% on activated carbon / methanol / 24 h / 50 °C / 30402 Torr

6.1: n-butyllithium / hexane; tetrahydrofuran / 0.5 h / -78 - 25 °C

6.2: 1 h / -78 - 25 °C

With triethylsilane; n-butyllithium; palladium 10% on activated carbon; boron trifluoride diethyl etherate; ethylmagnesium bromide; hydrogen; acetic acid; In tetrahydrofuran; methanol; hexane;
DOI:10.1016/j.ejmech.2014.06.016

Reference yield:

: 1620893-58-4
(4-(diethylamino)phenyl)(4-iodo-1-methyl-1H-imidazol-5-yl)methanol

: 1620893-68-6
4-((4-(3,4-bimethoxybenzyl)-2-azido-1-methyl-1H-imidazol-5-yl)methyl)-N,N-diethylbenzenamine

Guidance literature:: Multi-step reaction with 5 steps

1.1: triethylsilane; boron trifluoride diethyl etherate / tetrahydrofuran / 24 h / 0 - 60 °C / Inert atmosphere

2.1: ethylmagnesium bromide / tetrahydrofuran / 0.5 h / 25 °C / Inert atmosphere

2.2: 12 h / 25 °C / Inert atmosphere

3.1: tetrahydrofuran / 12 h / 25 °C / Inert atmosphere

4.1: acetic acid; hydrogen; palladium 10% on activated carbon / methanol / 24 h / 50 °C / 30402 Torr

5.1: n-butyllithium / hexane; tetrahydrofuran / 0.5 h / -78 - 25 °C

5.2: 1 h / -78 - 25 °C

With triethylsilane; n-butyllithium; palladium 10% on activated carbon; boron trifluoride diethyl etherate; ethylmagnesium bromide; hydrogen; acetic acid; In tetrahydrofuran; methanol; hexane;
DOI:10.1016/j.ejmech.2014.06.016