O-methyl (2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropiohydroxamate

Base Information

Chemical Name:O-methyl (2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropiohydroxamate
CAS No.:718615-71-5
Molecular Formula:C₂₁H₃₇NO₅Si
Molecular Weight:411.614
Hs Code.:

Synonyms:O-methyl (2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropiohydroxamate

Suppliers and Price of O-methyl (2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropiohydroxamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of O-methyl (2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropiohydroxamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of O-methyl (2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropiohydroxamate

There total 8 articles about O-methyl (2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropiohydroxamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 593-56-6
N-methoxylamine hydrochloride

: 718615-79-3
(2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropionic acid

: 718615-71-5
O-methyl (2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropiohydroxamate

Guidance literature:: (2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropionic acid; With triethylamine; isobutyl chloroformate; In dichloromethane; at -20 - 20 ℃; for 1h;

N-methoxylamine hydrochloride; With triethylamine; In dichloromethane; for 16h;
DOI:10.1021/jo051252r

Reference yield:

: 593-56-6
N-methoxylamine hydrochloride

: C₂₅H₄₂O₇Si

: 718615-71-5
O-methyl (2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropiohydroxamate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 16h;
DOI:10.1039/b403081h

Reference yield:

: 13154-24-0
triisopropylsilyl chloride

: 718615-71-5
O-methyl (2S)-3-(2,4-dimethoxyphenyl)-2-triisopropylsilanyloxypropiohydroxamate

Guidance literature:: Multi-step reaction with 4 steps

1: 99 percent / imidazole; DMAP / dimethylformamide / 36 h / 20 °C

2: 98 percent / KOH / methanol / 16 h / Heating

3: Et₃N / CH₂Cl₂ / 1 h / -20 - 20 °C

4: 358 mg / Et₃N / CH₂Cl₂ / 16 h / 20 °C

With 1H-imidazole; dmap; potassium hydroxide; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/b403081h