(S)-(3,5-Dimethoxy-phenyl)-trimethylsilanyloxy-acetonitrile

Base Information

• Chemical Name: (S)-(3,5-Dimethoxy-phenyl)-trimethylsilanyloxy-acetonitrile
• CAS No.: 224565-77-9
• Molecular Formula: C₁₃H₁₉NO₃Si
• Molecular Weight: 265.384
• Mol file: 224565-77-9.mol

Synonyms:(S)-(3,5-Dimethoxy-phenyl)-trimethylsilanyloxy-acetonitrile

Chemical Property of (S)-(3,5-Dimethoxy-phenyl)-trimethylsilanyloxy-acetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (S)-(3,5-Dimethoxy-phenyl)-trimethylsilanyloxy-acetonitrile

There total 1 articles about (S)-(3,5-Dimethoxy-phenyl)-trimethylsilanyloxy-acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trimethylsilyl cyanide (7677-24-9) + 3,5-dimethoxybenzaldehdye (7311-34-4) → (S)-(3,5-Dimethoxy-phenyl)-trimethylsilanyloxy-acetonitrile (224565-77-9) + (R)-(3,5-Dimethoxy-phenyl)-trimethylsilanyloxy-acetonitrile (156904-27-7)

Guidance literature:

titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; In dichloromethane; Yield given. Yields of byproduct given. Title compound not separated from byproducts; 1.) 0 deg C, 6 h, 2.) 25 deg C, 12 h;

DOI:10.1021/jo00093a021

Reference yield:

acetic anhydride (108-24-7) + (S)-(3,5-Dimethoxy-phenyl)-trimethylsilanyloxy-acetonitrile (224565-77-9) → (S)-cyano(3,5-dimethoxyphenyl)methyl acetate

Guidance literature:

With pyridine; In dichloromethane; at -78 - 20 ℃;

DOI:10.1021/ja051125c

upstream raw materials:

trimethylsilyl cyanide

3,5-dimethoxybenzaldehdye