Phenyl 2-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)cyclopropyl-carbamate

Base Information

Chemical Name:Phenyl 2-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)cyclopropyl-carbamate
CAS No.:1392425-70-5
Molecular Formula:C₂₅H₁₉F₃N₄O₃
Molecular Weight:480.446
Hs Code.:

Synonyms:Phenyl 2-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)cyclopropyl-carbamate

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Chemical Property of Phenyl 2-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)cyclopropyl-carbamate

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Technology Process of Phenyl 2-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)cyclopropyl-carbamate

There total 3 articles about Phenyl 2-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)cyclopropyl-carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1392425-84-1
2-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)cyclopropanecarbonyl azide

: 108-95-2,27073-41-2
phenol

: 1392425-70-5
Phenyl 2-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)cyclopropyl-carbamate

Guidance literature:: 2-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)cyclopropanecarbonyl azide; phenol; In toluene; at 100 ℃; for 2h;

With triethylamine; In toluene; at 25 ℃;

Reference yield:

: (x)C₂HF₃O₂*C₁₉H₁₄F₃N₃O₃

: 1392425-70-5
Phenyl 2-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)cyclopropyl-carbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine; diphenylphosphoranyl azide / toluene / 2 h / 25 °C

2.1: toluene / 2 h / 100 °C

2.2: 25 °C

With diphenylphosphoranyl azide; triethylamine; In toluene;

Reference yield:

: 1392425-83-0
2-{4-[1-(4-trifluoromethoxyphenyl)-1H-[1,2,4]triazol-3-yl]phenyl}cyclopropanecarboxylic acid tert-butyl ester

: 1392425-70-5
Phenyl 2-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)cyclopropyl-carbamate

Guidance literature:: Multi-step reaction with 3 steps

1.1: dichloromethane / 18 h / 25 °C

2.1: triethylamine; diphenylphosphoranyl azide / toluene / 2 h / 25 °C

3.1: toluene / 2 h / 100 °C

3.2: 25 °C

With diphenylphosphoranyl azide; triethylamine; In dichloromethane; toluene;