2,5-bis(4-nitrophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-pyrrole

Base Information

• Chemical Name: 2,5-bis(4-nitrophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-pyrrole
• CAS No.: 1258233-38-3
• Molecular Formula: C₂₃H₁₄F₃N₃O₄
• Molecular Weight: 453.377
• Mol file: 1258233-38-3.mol

Synonyms:2,5-bis(4-nitrophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-pyrrole

Chemical Property of 2,5-bis(4-nitrophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-pyrrole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2,5-bis(4-nitrophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-pyrrole

There total 2 articles about 2,5-bis(4-nitrophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.9%

4-trifluoromethylphenylamine (455-14-1) + 1,4‐bis(4‐nitrophenyl)butane‐1,4‐dione (108791-66-8) → 2,5-bis(4-nitrophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-pyrrole (1258233-38-3)

Guidance literature:

With trifluoroacetic acid; In toluene; at 110 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c6ra11615a

Reference yield:

4-Nitrophenacyl bromide (99-81-0) → 2,5-bis(4-nitrophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-pyrrole (1258233-38-3)

Guidance literature:

Multi-step reaction with 2 steps

1: rongalite / N,N-dimethyl-formamide

2: trifluoroacetic acid / toluene / 24 h / 110 °C / Inert atmosphere

With rongalite; trifluoroacetic acid; In N,N-dimethyl-formamide; toluene;

DOI:10.1039/c6ra11615a

Reference yield: 75.3%

2,5-bis(4-nitrophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-pyrrole (1258233-38-3) → 4,40-(1-(4-(trifluoromethyl)phenyl)-1H-pyrrole-2,5-diyl)dianiline

Guidance literature:

With tin(II) chloride dihdyrate; In ethyl acetate; for 4h; Reflux; Inert atmosphere;

DOI:10.1039/c6ra11615a

upstream raw materials:

4-trifluoromethylphenylamine

1,4‐bis(4‐nitrophenyl)butane‐1,4‐dione

4-Nitrophenacyl bromide