2-METHYL-BENZAMIDINE

Base Information

• Chemical Name: 2-METHYL-BENZAMIDINE
• CAS No.: 18636-97-0
• Molecular Formula: C8H10 N2
• Molecular Weight: 134.181
• Hs Code.: 2925290090
• Mol file: 18636-97-0.mol

Synonyms:o-Toluamidine(8CI); 2-Methylbenzamidine

Chemical Property of 2-METHYL-BENZAMIDINE

Chemical Property:

• Vapor Pressure: 0.0604mmHg at 25°C
• Melting Point: 205-207 °C
• Refractive Index: 1.559
• Boiling Point: 232°C at 760 mmHg
• PKA: 12.02±0.40(Predicted)
• Flash Point: 94.1°C
• PSA: 49.87000
• Density: 1.07g/cm³
• LogP: 2.07910

Purity/Quality:

97% ^*data from raw suppliers

2-Methyl-Benzamidine 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHYL-BENZAMIDINE

There total 4 articles about 2-METHYL-BENZAMIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N'-hydroxy-2-methylbenzamidine (40312-14-9) → 2-methylbenzamidine (18636-97-0)

Guidance literature:

With hydrogen; nickel; In ethanol;

DOI:10.1021/jm00309a029

Reference yield:

2-Methylbenzonitrile (529-19-1) → 2-methylbenzamidine (18636-97-0)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOEt, NH₂OH*HCl / aq. ethanol / Heating

2: H₂ / Raney-Ni / ethanol

With hydroxylamine hydrochloride; hydrogen; sodium ethanolate; nickel; In ethanol;

DOI:10.1021/jm00309a029

Reference yield:

ethoxy(2-methylphenyl)methaniminium tetrafluoroborate → 2-methylbenzamidine (18636-97-0)

Guidance literature:

With ammonia; In ethanol;

DOI:10.1021/jo01268a093

upstream raw materials:

N'-hydroxy-2-methylbenzamidine

2-Methylbenzonitrile

Downstream raw materials:

2-methylbenzimidamide hydrochloride