5,7,3',4'-tetra-O-methylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin)

Base Information

• Chemical Name: 5,7,3',4'-tetra-O-methylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin)
• CAS No.: 37064-32-7
• Molecular Formula: C₃₈H₄₂O₁₂
• Molecular Weight: 690.744
• Mol file: 37064-32-7.mol

Synonyms:5,7,3',4'-tetra-O-methylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin)

Chemical Property of 5,7,3',4'-tetra-O-methylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,7,3',4'-tetra-O-methylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin)

There total 7 articles about 5,7,3',4'-tetra-O-methylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

dimethyl sulfate (77-78-1) + 5,7,3',4'-tetra-O-benzylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin) (299412-75-2) → 5,7,3',4'-tetra-O-methylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin) (37064-32-7)

Guidance literature:

5,7,3',4'-tetra-O-benzylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin); With hydrogen; palladium dihydroxide; In methanol; ethyl acetate; at 20 ℃; under 750.075 Torr;

dimethyl sulfate; With potassium carbonate; at 60 ℃; for 4h; Further stages.;

DOI:10.1021/jo000485+

Reference yield: 41.0%

procyanidin B2 (29106-49-8) + dimethyl sulfate (77-78-1) → 5,7,3',4'-tetra-O-methylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin) (37064-32-7)

Guidance literature:

With potassium carbonate; In various solvent(s); at 60 ℃; for 4h;

DOI:10.1021/jo000485+

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + procyanidin B2 (29106-49-8) → 5,7,3',4'-tetra-O-methylepicatechin-4β,8-(5,7,3',4'-tetra-O-methylepicatechin) (37064-32-7)

Guidance literature:

In methanol; diethyl ether; at -15 ℃; for 48h;

upstream raw materials:

diazomethane

procyanidin B₂

(2R,3R,4S)-2,3-cis-3,4-trans-3',4',5,7-tetramethoxyflavan-3,4-diol

(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol

Downstream raw materials:

(2R,3R)-2,3-cis-3-acetoxy-8-<(2R,3R,4R)-2,3-cis-3,4-trans-3-acetoxy-3',4',5,7-tetramethoxyflavan-4-yl>-3',4',5,7-tetramethoxyflavan