2-BROMO-3-METHYLBUTANE

Base Information

• Chemical Name: 2-BROMO-3-METHYLBUTANE
• CAS No.: 18295-25-5
• Molecular Formula: C₅H₁₁Br
• Molecular Weight: 151.046
• Mol file: 18295-25-5.mol

Synonyms:2-Bromo-3-methylbutane

Chemical Property of 2-BROMO-3-METHYLBUTANE

Chemical Property:

• Vapor Pressure: 29.8mmHg at 25°C
• Melting Point: -105.4°C (estimate)
• Refractive Index: 1.438
• Boiling Point: 108.9°C at 760 mmHg
• Flash Point: 21.6°C
• PSA: 0.00000
• Density: 1.208g/cm³
• LogP: 2.42580

Purity/Quality:

99% ^*data from raw suppliers

2-Bromo-3-methylbutane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R10-36/37/38:
• Hazard Codes: R10-36/37/38:
• Statements: 10-36/37/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Bromo-3-methylbutane is a reagent used in the synthesis of various sterols. Also used in the preparation of organic fluorine compounds as insecticides and rodenticides.

Technology Process of 2-BROMO-3-METHYLBUTANE

There total 25 articles about 2-BROMO-3-METHYLBUTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

3-methyl-2-butanol (598-75-4) → 3-bromo-2-methylbutane (18295-25-5,26561-37-5)

Guidance literature:

With hydrogen bromide; Aliquat 336; In chlorobenzene; at 85 ℃;

DOI:10.1016/S0040-4039(00)95331-0

Reference yield:

methylbutane (78-78-4) → 1-bromo-2-methyl-butane (10422-35-2,99032-67-4,534-00-9,5973-11-5) + 2-bromo-2-methylbutane (507-36-8) + 3-bromo-2-methylbutane (18295-25-5,26561-37-5) + i-pentyl bromide (107-82-4)

Guidance literature:

With norborn-2-ene; N-bromobis(trimethylsilyl)amine; at 59.9 ℃; for 1.16667h; Mechanism; Product distribution; Irradiation; variation of temperature, time, reagent, initiation; further hydrocarbons;

Reference yield:

2-bromo-2-methylbutane (507-36-8) → 1-bromo-2-methyl-butane (10422-35-2,99032-67-4,534-00-9,5973-11-5) + 3-bromo-2-methylbutane (18295-25-5,26561-37-5) + i-pentyl bromide (107-82-4)

Guidance literature:

at 220 ℃;

upstream raw materials:

2-methyl-but-2-ene

3-methyl-2-butanol

(S)-2-methylbutyl bromide

2-bromo-2-methylbutane

Downstream raw materials:

3,4-Dimethylpentanoic acid

2-bromo-2-methylbutane

3-Methyl-1-butene

(2RS,3RS)-2-amino-3-methylhexanoic acid

Refernces

• 1、 Bartlett,Condon,Schneider. "-". . p. 1531,1538. Retrieved 1944.
• 2、 Inomoto,Y. et al.. "-". . p. 4599 - 4605. Retrieved 1969.
• 3、 Dakka, Gihad,Sasson, Yoel. "SELECTIVE HYDROBROMINATION OF BRANCHED ALCOHOLS USING PHASE TRANSFER CATALYSIS". . p. 1223 - 1224. Retrieved 2007/10/02.