5-(4-Chloro-phenyl)-1-((Z)-1,2-diphenyl-2-phenylamino-vinyl)-1H-pyrrole-2,3,4-tricarboxylic acid 2-ethoxycarbonylmethyl ester 3,4-dimethyl ester

Base Information

• Chemical Name: 5-(4-Chloro-phenyl)-1-((Z)-1,2-diphenyl-2-phenylamino-vinyl)-1H-pyrrole-2,3,4-tricarboxylic acid 2-ethoxycarbonylmethyl ester 3,4-dimethyl ester
• CAS No.: 150536-84-8
• Molecular Formula: C₃₉H₃₃ClN₂O₈
• Molecular Weight: 693.153
• Mol file: 150536-84-8.mol

Synonyms:5-(4-Chloro-phenyl)-1-((Z)-1,2-diphenyl-2-phenylamino-vinyl)-1H-pyrrole-2,3,4-tricarboxylic acid 2-ethoxycarbonylmethyl ester 3,4-dimethyl ester

Chemical Property of 5-(4-Chloro-phenyl)-1-((Z)-1,2-diphenyl-2-phenylamino-vinyl)-1H-pyrrole-2,3,4-tricarboxylic acid 2-ethoxycarbonylmethyl ester 3,4-dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 5-(4-Chloro-phenyl)-1-((Z)-1,2-diphenyl-2-phenylamino-vinyl)-1H-pyrrole-2,3,4-tricarboxylic acid 2-ethoxycarbonylmethyl ester 3,4-dimethyl ester

There total 2 articles about 5-(4-Chloro-phenyl)-1-((Z)-1,2-diphenyl-2-phenylamino-vinyl)-1H-pyrrole-2,3,4-tricarboxylic acid 2-ethoxycarbonylmethyl ester 3,4-dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

dimethyl acetylenedicarboxylate (762-42-5) + 5-(4-Chloro-phenyl)-1-ethoxycarbonylmethyl-2,3,4-triphenyl-2H-pyrazol-1-ium; perchlorate → 6-(4-Chloro-phenyl)-1-oxo-2,3,4-triphenyl-1,2-dihydro-pyrrolo[1,2-a]pyrazine-7,8-dicarboxylic acid dimethyl ester + 5-(4-Chloro-phenyl)-1-((Z)-1,2-diphenyl-2-phenylamino-vinyl)-1H-pyrrole-2,3,4-tricarboxylic acid 2-ethoxycarbonylmethyl ester 3,4-dimethyl ester (150536-84-8)

Guidance literature:

With potassium carbonate; In toluene; at 100 ℃; for 48h;

DOI:10.1039/P19930000883

Reference yield:

3-(4-chlorophenyl)-1,4,5-triphenyl-1H-pyrazole → 5-(4-Chloro-phenyl)-1-((Z)-1,2-diphenyl-2-phenylamino-vinyl)-1H-pyrrole-2,3,4-tricarboxylic acid 2-ethoxycarbonylmethyl ester 3,4-dimethyl ester (150536-84-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 2) NaClO₄ / 1) heating, 2) ethanol

2: 44 percent / K₂CO₃ / toluene / 48 h / 100 °C

With sodium perchlorate; potassium carbonate; In toluene;

DOI:10.1039/P19930000883

Reference yield: 86.0%

5-(4-Chloro-phenyl)-1-((Z)-1,2-diphenyl-2-phenylamino-vinyl)-1H-pyrrole-2,3,4-tricarboxylic acid 2-ethoxycarbonylmethyl ester 3,4-dimethyl ester (150536-84-8) → 6-(4-Chloro-phenyl)-1-oxo-2,3,4-triphenyl-1,2-dihydro-pyrrolo[1,2-a]pyrazine-7,8-dicarboxylic acid dimethyl ester

Guidance literature:

With potassium carbonate; In toluene; for 48h; Heating;

DOI:10.1039/P19930000883

upstream raw materials:

dimethyl acetylenedicarboxylate