1H-Benzimidazole,2-(2-pyrimidinyl)-(9CI)

Base Information

• Chemical Name: 1H-Benzimidazole,2-(2-pyrimidinyl)-(9CI)
• CAS No.: 18107-02-3
• Molecular Formula: C11H8 N4
• Molecular Weight: 196.21
• Hs Code.: 2933990090
• Mol file: 18107-02-3.mol

Synonyms:Benzimidazole,2-(2-pyrimidinyl)- (8CI)

Chemical Property of 1H-Benzimidazole,2-(2-pyrimidinyl)-(9CI)

Chemical Property:

• PSA: 54.46000
• LogP: 2.01990
• Storage Temp.: 2-8°C

Purity/Quality:

2-(Pyrimidin-2-yl)-1H-benzo[d]imidazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Benzimidazole,2-(2-pyrimidinyl)-(9CI)

There total 2 articles about 1H-Benzimidazole,2-(2-pyrimidinyl)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-cyanopyrimidine (14080-23-0) + 1,2-diamino-benzene (95-54-5) → 2-(benzimidazol-2-yl)pyrimidine (18107-02-3)

Guidance literature:

at 160 ℃; for 2h; Inert atmosphere;

Reference yield:

→ 2-(benzimidazol-2-yl)pyrimidine (18107-02-3)

Guidance literature:

3-Cyan-pyrimidin, o-Phenylendiamin, Polyphosphorsaeure, 250grad;

Reference yield: 70.0%

potassium hexafluorophosphate (17084-13-8) + chloro[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]copper(I) (578743-87-0) + 2-(benzimidazol-2-yl)pyrimidine (18107-02-3) → C65H79Cu2N8(1+)*F6P(1-)

Guidance literature:

2-(benzimidazol-2-yl)pyrimidine; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 1h; Schlenk technique; Inert atmosphere;

chloro[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]copper(I); In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere; Schlenk technique;

potassium hexafluorophosphate; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere; Schlenk technique;

DOI:10.1039/C8DT04007A

upstream raw materials:

2-cyanopyrimidine

1,2-diamino-benzene

Refernces

• 1、 Haga, Masa-Aki,Ishizuya, Masahide,Kanesugi, Tomokazu,Yutaka, Tomona,Sakiyama, Daisuke,Fees, Joerg,Kaim, Wolfgang. "Synthesis and formation of dinuclear mixed-valent complexes of ruthenium and osmium bridged by 2-(2-pyrimidyl)benzimidazolate". . p. 2290 - 2299. Retrieved 2007/10/03.