(+)-6-O-allyl-1-O-(p-methoxybenzyl)-4,5-di-O-benzyl-myo-inositol

Base Information

• Chemical Name: (+)-6-O-allyl-1-O-(p-methoxybenzyl)-4,5-di-O-benzyl-myo-inositol
• CAS No.: 475650-91-0
• Molecular Formula: C₃₁H₃₆O₇
• Molecular Weight: 520.623
• Mol file: 475650-91-0.mol

Synonyms:(+)-6-O-allyl-1-O-(p-methoxybenzyl)-4,5-di-O-benzyl-myo-inositol

Chemical Property of (+)-6-O-allyl-1-O-(p-methoxybenzyl)-4,5-di-O-benzyl-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-6-O-allyl-1-O-(p-methoxybenzyl)-4,5-di-O-benzyl-myo-inositol

There total 9 articles about (+)-6-O-allyl-1-O-(p-methoxybenzyl)-4,5-di-O-benzyl-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C37H44O7 (475650-90-9) → (+)-6-O-allyl-1-O-(p-methoxybenzyl)-4,5-di-O-benzyl-myo-inositol (475650-91-0)

Guidance literature:

With methanol; acetyl chloride; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/S0960-894X(02)00301-3

Reference yield:

(+)-1,2:5,6-di-O-cyclohexylidene-myo-inositol (41545-19-1) → (+)-6-O-allyl-1-O-(p-methoxybenzyl)-4,5-di-O-benzyl-myo-inositol (475650-91-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: Bu₂SnO / toluene / 2.5 h / Heating

1.2: 80 percent / CsF / dimethylformamide / 16 h / 20 °C

2.1: 85 percent / NaH / dimethylformamide / 3 h / 20 °C

3.1: 60 percent / acetyl chloride / methanol; CH₂Cl₂ / 0.17 h / 20 °C

4.1: NaH / dimethylformamide / 3 h / 20 °C

5.1: 0.97 g / acetyl chloride / methanol; CH₂Cl₂ / 2 h / 20 °C

With sodium hydride; di(n-butyl)tin oxide; acetyl chloride; In methanol; dichloromethane; N,N-dimethyl-formamide; toluene;

DOI:10.1021/jo034213t

Reference yield:

(-)-6-O-allyl-1-O-(p-methoxybenzyl)-2,3-O-cyclohexylidene-myo-inositol (211799-72-3) → (+)-6-O-allyl-1-O-(p-methoxybenzyl)-4,5-di-O-benzyl-myo-inositol (475650-91-0)

Guidance literature:

Multi-step reaction with 2 steps

1: NaH / dimethylformamide / 3 h / 20 °C

2: 0.97 g / acetyl chloride / methanol; CH₂Cl₂ / 2 h / 20 °C

With sodium hydride; acetyl chloride; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo034213t

upstream raw materials:

C₃₇H₄₄O₇

(+)-1,2:5,6-di-O-cyclohexylidene-myo-inositol

(+/-)-1,2:5,6-dicyclohexylidene-myo-inositol

(+)-6-O-butyryl-2,3:4,5-di-O-cyclohexylidene-myo-inositol

Downstream raw materials:

1D-6-O-allyl-3,4,5-tri-O-benzyl-1-O-(4-methoxybenzoyl)-myo-inositol

6-O-[2-azido-3,6-di-O-benzyl-2-deoxy-4-O-(2-propenyl)-α-D-glucopyranosyl]-2-O-hexadecanoyl-3,4,5-tri-O-benzyl-myo-inositol

6-O-(2-azido-3,6-di-O-benzyl-2-deoxy-α-D-glucopyranosyl)-2-O-hexadecanoyl-1-O-(p-methoxybenzyl)-3,4,5-tri-O-benzyl-myo-inositol

6-O-[2-azido-3,6-di-O-benzyl-2-deoxy-4-O-(2-propenyl)-α-D-glucopyranosyl]-2-O-hexadecanoyl-1-O-(p-methoxybenzyl)-3,4,5-tri-O-benzyl-myo-inositol