3,4-DIMETHYL-3-CYCLOHEXENYLMETHANAL

Base Information

• Chemical Name: 3,4-DIMETHYL-3-CYCLOHEXENYLMETHANAL
• CAS No.: 18022-66-7
• Molecular Formula: C9H14 O
• Molecular Weight: 138.21
• Hs Code.: 2912299000
• Mol file: 18022-66-7.mol

Synonyms:1,2-Dimethyl-4-formyl-1-cyclohexene;3,4-Dimethyl-D3-tetrahydrobenzaldehyde

Chemical Property of 3,4-DIMETHYL-3-CYCLOHEXENYLMETHANAL

Chemical Property:

• Refractive Index: n20/D1.477-1.481
• Boiling Point: 79°C/10mmHg(lit.)
• PSA: 17.07000
• Density: 0.971±0.06 g/cm3(Predicted)
• LogP: 2.32180
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

3,4-Dimethyl-3-cyclohexenecarboxaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3,4-Dimethyl-3-cyclohexenecarboxaldehyde is used in preparation of secondary Amine compounds as tRNA synthetase inhibitors useful in killing Gram-negative bacteria.

Technology Process of 3,4-DIMETHYL-3-CYCLOHEXENYLMETHANAL

There total 12 articles about 3,4-DIMETHYL-3-CYCLOHEXENYLMETHANAL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3-dimethyl-buta-1,3-diene (513-81-5) + acrolein (107-02-8,25068-14-8) → 3,4-dimethylcyclohex-3-ene-1-carboxaldehyde (18022-66-7)

Guidance literature:

With trityl tetrafluoroborate; In dichloromethane; at 20 ℃; for 48h;

DOI:10.1002/chem.201304160

Reference yield: 99.0%

2,3-dimethyl-buta-1,3-diene (513-81-5) + acrolein (107-02-8,25068-14-8) → (R)-3,4-dimethylcyclohex-3-enecarbaldehyde (18022-66-7)

Guidance literature:

acrolein; With ionic chiral polyester functionalized chiral imidazolidinone p-toluenesulfonate; In methanol; water; at 25 ℃; for 0.166667h;

2,3-dimethyl-buta-1,3-diene; In methanol; water; at 25 ℃; for 24h; enantioselective reaction;

DOI:10.1002/cctc.201700723

Reference yield: 94.0%

2,3-dimethyl-buta-1,3-diene (513-81-5) + acrolein (107-02-8,25068-14-8) → (S)-3,4-Dimethyl-cyclohex-3-enecarbaldehyde (18022-66-7)

Guidance literature:

With 13c-TFA; In methanol; water; at 20 ℃; for 24h;

DOI:10.1002/adsc.201500539

upstream raw materials:

2,3-dimethyl-buta-1,3-diene

acrolein

2,3-dimethyl-2,3-butane diol

Downstream raw materials:

(3,4-dimethylcyclohex-3-en-1-yl)methanol

1-(3,4-Dimethyl-cyclohex-3-enyl)-but-3-en-1-ol

(4R,6R)-2-((R)-3,4-Dimethyl-cyclohex-3-enyl)-4,6-dimethyl-[1,3]dioxane

(4R,6R)-2-((S)-3,4-Dimethyl-cyclohex-3-enyl)-4,6-dimethyl-[1,3]dioxane