1,2,3,3a,4,5-Hexahydropyrrolo[1,2-a]quinoxaline

Base Information

Chemical Name:1,2,3,3a,4,5-Hexahydropyrrolo[1,2-a]quinoxaline
CAS No.:18019-17-5
Molecular Formula:C₁₁H₁₄N₂
Molecular Weight:174.246
Hs Code.:
European Community (EC) Number:863-586-4
ChEMBL ID:CHEMBL45637
Mol file:18019-17-5.mol

Synonyms:1,2,3,3a,4,5-hexahydropyrrolo[1,2-a]quinoxaline;18019-17-5;Pyrrolo[1,2-a]quinoxaline, 1,2,3,3a,4,5-hexahydro- (8CI,9CI);1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline;MLS001198985;CHEMBL45637;SCHEMBL7985244;IZAIOGMVPVWOKY-UHFFFAOYSA-N;HMS1630C08;HMS2851E21;(-)-1,2,3,3A,4,5-HEXAHYDRO-PYRROLO[1,2-A]QUINOXALINE;AKOS001855812;AKOS022203130;SMR000563166;EN300-39161;G44500;Z382687448

Suppliers and Price of 1,2,3,3a,4,5-Hexahydropyrrolo[1,2-a]quinoxaline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline
250mg
$ 350.00

TRC
1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline
50mg
$ 90.00

American Custom Chemicals Corporation
1,2,3,3A,4,5-HEXAHYDROPYRROLO[1,2-A]QUINOXALINE 95.00%
5G
$ 1759.28

American Custom Chemicals Corporation
1,2,3,3A,4,5-HEXAHYDROPYRROLO[1,2-A]QUINOXALINE 95.00%
2.5G
$ 1363.65

American Custom Chemicals Corporation
1,2,3,3A,4,5-HEXAHYDROPYRROLO[1,2-A]QUINOXALINE 95.00%
1G
$ 925.31

AK Scientific
1,2,3,3a,4,5-Hexahydropyrrolo[1,2-a]quinoxaline
10g
$ 2332.00

Total 3 raw suppliers

Chemical Property of 1,2,3,3a,4,5-Hexahydropyrrolo[1,2-a]quinoxaline

Chemical Property:

PSA：15.27000
LogP:2.28390
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:174.115698455
Heavy Atom Count:13
Complexity:193

Purity/Quality:

99% ^*data from raw suppliers

1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2CNC3=CC=CC=C3N2C1

Technology Process of 1,2,3,3a,4,5-Hexahydropyrrolo[1,2-a]quinoxaline

There total 5 articles about 1,2,3,3a,4,5-Hexahydropyrrolo[1,2-a]quinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 21550-86-7
1,2,3,3a-tetrahydro-5H-pyrrolo[1,2-a]quinoxalin-4-one

: 92622-53-2,18019-17-5,214353-19-2,214353-20-5
1,2,3,3a,4,5-hexahydropyrrolo<1,2-a>quinoxaline

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; for 18h; Heating;
DOI:10.1021/jm00378a039

Reference yield:

: 88-73-3
2-Chloronitrobenzene

: 92622-53-2,18019-17-5,214353-19-2,214353-20-5
1,2,3,3a,4,5-hexahydropyrrolo<1,2-a>quinoxaline

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / triethylamine / dimethylsulfoxide / 18 h / 60 °C

2: glacial acetic acid, iron powder / 3 h / 60 - 65 °C

3: 80 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 18 h / Heating

With lithium aluminium tetrahydride; iron; acetic acid; triethylamine; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide;
DOI:10.1021/jm00378a039

Reference yield:

: 31981-54-1
(S)-N-(2-nitrophenyl)proline

: 92622-53-2,18019-17-5,214353-19-2,214353-20-5
1,2,3,3a,4,5-hexahydropyrrolo<1,2-a>quinoxaline

Guidance literature:: Multi-step reaction with 2 steps

1: glacial acetic acid, iron powder / 3 h / 60 - 65 °C

2: 80 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 18 h / Heating

With lithium aluminium tetrahydride; iron; acetic acid; In tetrahydrofuran; diethyl ether;
DOI:10.1021/jm00378a039