ethyl 3-(1-(4-carbamoyl-2-methylphenyl)-5-(4-(2-oxooxazolidin-3-yl)phenyl)-1H-pyrrol-2-yl)propanoate

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Chemical Name:ethyl 3-(1-(4-carbamoyl-2-methylphenyl)-5-(4-(2-oxooxazolidin-3-yl)phenyl)-1H-pyrrol-2-yl)propanoate
CAS No.:1208318-56-2
Molecular Formula:C₂₆H₂₇N₃O₅
Molecular Weight:461.517
Hs Code.:

Synonyms:ethyl 3-(1-(4-carbamoyl-2-methylphenyl)-5-(4-(2-oxooxazolidin-3-yl)phenyl)-1H-pyrrol-2-yl)propanoate

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Chemical Property of ethyl 3-(1-(4-carbamoyl-2-methylphenyl)-5-(4-(2-oxooxazolidin-3-yl)phenyl)-1H-pyrrol-2-yl)propanoate

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Technology Process of ethyl 3-(1-(4-carbamoyl-2-methylphenyl)-5-(4-(2-oxooxazolidin-3-yl)phenyl)-1H-pyrrol-2-yl)propanoate

There total 5 articles about ethyl 3-(1-(4-carbamoyl-2-methylphenyl)-5-(4-(2-oxooxazolidin-3-yl)phenyl)-1H-pyrrol-2-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 1208318-55-1
ethyl 4,7-dioxo-7-(4-(2-oxooxazolidin-3-yl)phenyl)heptanoate

: 106037-36-9
4-amino-3-methylbenzamide

: 1208318-56-2
ethyl 3-(1-(4-carbamoyl-2-methylphenyl)-5-(4-(2-oxooxazolidin-3-yl)phenyl)-1H-pyrrol-2-yl)propanoate

Guidance literature:: With zinc trifluoromethanesulfonate; In ethanol; at 120 ℃; for 2h; Microwave irradiation;
DOI:10.1016/j.bmcl.2011.07.103

Reference yield:

: 1208318-08-4
ethyl 7-(4-bromophenyl)-4,7-dioxoheptanoate

: 1208318-56-2
ethyl 3-(1-(4-carbamoyl-2-methylphenyl)-5-(4-(2-oxooxazolidin-3-yl)phenyl)-1H-pyrrol-2-yl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) iodide; potassium carbonate; L-proline / 1,4-dioxane / 48 h / 110 °C / Inert atmosphere

2: zinc trifluoromethanesulfonate / ethanol / 2 h / 120 °C / Microwave irradiation

With copper(l) iodide; zinc trifluoromethanesulfonate; potassium carbonate; L-proline; In 1,4-dioxane; ethanol;
DOI:10.1016/j.bmcl.2011.07.103

Reference yield:

: 98-01-1
furfural

: 1208318-56-2
ethyl 3-(1-(4-carbamoyl-2-methylphenyl)-5-(4-(2-oxooxazolidin-3-yl)phenyl)-1H-pyrrol-2-yl)propanoate

Guidance literature:: Multi-step reaction with 4 steps

1: methanol; sodium methylate / 20 °C

2: hydrogen bromide / water; ethanol / 8 h / Reflux

3: L-proline; copper(l) iodide; potassium carbonate / 1,4-dioxane / 48 h / 110 °C / Inert atmosphere

4: zinc trifluoromethanesulfonate / ethanol / 2 h / 120 °C / Microwave irradiation

With methanol; copper(l) iodide; hydrogen bromide; sodium methylate; zinc trifluoromethanesulfonate; potassium carbonate; L-proline; In 1,4-dioxane; ethanol; water;