Ethyl 7-(4-bromophenyl)-4,7-dioxoheptanoate

Base Information

• Chemical Name: Ethyl 7-(4-bromophenyl)-4,7-dioxoheptanoate
• CAS No.: 1208318-08-4
• Molecular Formula: C15H17BrO4
• Molecular Weight: 341.202
• Mol file: 1208318-08-4.mol

Synonyms:-4,7-dioxoheptanoate;Ethyl 7-(4-bromophenyl);Ethyl 7-(4-broMophenyl)-4,7-dioxoheptanoate

Chemical Property of Ethyl 7-(4-bromophenyl)-4,7-dioxoheptanoate

Chemical Property:

• PSA: 60.44000
• LogP: 3.32440
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 7-(4-bromophenyl)-4,7-dioxoheptanoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethyl 7-(4-bromophenyl)-4,7-dioxoheptanoate

There total 4 articles about Ethyl 7-(4-bromophenyl)-4,7-dioxoheptanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

1-(4-bromophenyl)-3-(furan-2-yl)-2-propen-1-one (132434-53-8,36715-58-9) → ethyl 7-(4-bromophenyl)-4,7-dioxoheptanoate (1208318-08-4)

Guidance literature:

With hydrogen bromide; In ethanol; water; for 8h; Reflux;

Reference yield:

furfural (98-01-1) → ethyl 7-(4-bromophenyl)-4,7-dioxoheptanoate (1208318-08-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium methylate / methanol / 20 °C

2: hydrogen bromide / 8 h / Reflux

With hydrogen bromide; sodium methylate; In methanol;

DOI:10.1016/j.bmcl.2012.01.047

Reference yield:

para-bromoacetophenone (99-90-1) → ethyl 7-(4-bromophenyl)-4,7-dioxoheptanoate (1208318-08-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium methylate / methanol / 20 °C

2: hydrogen bromide / 8 h / Reflux

With hydrogen bromide; sodium methylate; In methanol;

DOI:10.1016/j.bmcl.2012.01.047

upstream raw materials:

furfural

1-(4-bromophenyl)-3-(furan-2-yl)-2-propen-1-one

ethanol

para-bromoacetophenone

Downstream raw materials:

ethyl 4,7-dioxo-7-(4-(2-oxooxazolidin-3-yl)phenyl)heptanoate

ethyl 3-(1-(4-carbamoyl-2-methylphenyl)-5-(4-(2-oxooxazolidin-3-yl)phenyl)-1H-pyrrol-2-yl)propanoate

3-(1-(4-carbamoyl-2-methylphenyl)-5-(4-(2-oxooxazolidin-3-yl)phenyl)-1H-pyrrol-2-yl)propanoic acid

ethyl 3-(5-(4-bromophenyl)-1-(4-carbamoyl-2-methylphenyl)-1H-pyrrol-2-yl)propanoate