5,6,7,8-tetrahydro-5-hydroxy-2-(phenylmethoxy)-5-(phenylmethyl)quinoline

Base Information

Chemical Name:5,6,7,8-tetrahydro-5-hydroxy-2-(phenylmethoxy)-5-(phenylmethyl)quinoline
CAS No.:143246-84-8
Molecular Formula:C₂₃H₂₃NO₂
Molecular Weight:345.441
Hs Code.:

Synonyms:5,6,7,8-tetrahydro-5-hydroxy-2-(phenylmethoxy)-5-(phenylmethyl)quinoline

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Chemical Property of 5,6,7,8-tetrahydro-5-hydroxy-2-(phenylmethoxy)-5-(phenylmethyl)quinoline

Chemical Property:

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Safty Information:

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Technology Process of 5,6,7,8-tetrahydro-5-hydroxy-2-(phenylmethoxy)-5-(phenylmethyl)quinoline

There total 4 articles about 5,6,7,8-tetrahydro-5-hydroxy-2-(phenylmethoxy)-5-(phenylmethyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5,6,7,8-tetrahydro-5-oxo-2-(phenylmethoxy)quinolinone

: 6921-34-2
benzylmagnesium chloride

: 143246-84-8
5,6,7,8-tetrahydro-5-hydroxy-2-(phenylmethoxy)-5-(phenylmethyl)quinoline

Guidance literature:: With ammonium chloride; In diethyl ether; toluene;

Reference yield:

: 15450-69-8
5,6,7,8-tetrahydro-5-oxo-2(1H)-quinolinone

: 143246-84-8
5,6,7,8-tetrahydro-5-hydroxy-2-(phenylmethoxy)-5-(phenylmethyl)quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: silver carbonate / toluene / 68 h / Ambient temperature

2: diethyl ether; toluene / Ambient temperature

With silver carbonate; In diethyl ether; toluene;
DOI:10.1021/jm00018a025

Reference yield:

: 100-39-0
benzyl bromide

: 143246-84-8
5,6,7,8-tetrahydro-5-hydroxy-2-(phenylmethoxy)-5-(phenylmethyl)quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: silver carbonate / toluene / 68 h / Ambient temperature

2: diethyl ether; toluene / Ambient temperature

With silver carbonate; In diethyl ether; toluene;
DOI:10.1021/jm00018a025