5-(3,4-difluorophenyl)-3-cyclopropylimino-2-(2-methoxy-3-pyridyl)amino-3,5-dihydrophenazine

Base Information

Chemical Name:5-(3,4-difluorophenyl)-3-cyclopropylimino-2-(2-methoxy-3-pyridyl)amino-3,5-dihydrophenazine
CAS No.:1353740-16-5
Molecular Formula:C₂₇H₂₁F₂N₅O
Molecular Weight:469.493
Hs Code.:

Synonyms:5-(3,4-difluorophenyl)-3-cyclopropylimino-2-(2-methoxy-3-pyridyl)amino-3,5-dihydrophenazine

Suppliers and Price of 5-(3,4-difluorophenyl)-3-cyclopropylimino-2-(2-methoxy-3-pyridyl)amino-3,5-dihydrophenazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-(3,4-difluorophenyl)-3-cyclopropylimino-2-(2-methoxy-3-pyridyl)amino-3,5-dihydrophenazine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(3,4-difluorophenyl)-3-cyclopropylimino-2-(2-methoxy-3-pyridyl)amino-3,5-dihydrophenazine

There total 9 articles about 5-(3,4-difluorophenyl)-3-cyclopropylimino-2-(2-methoxy-3-pyridyl)amino-3,5-dihydrophenazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5-(3,4-difluorophenyl)-3-imino-2-(2-methoxy-3-pyridyl)amino-3,5-dihydrophenazine

: 765-30-0
Cyclopropylamine

: 1353740-16-5
5-(3,4-difluorophenyl)-3-cyclopropylimino-2-(2-methoxy-3-pyridyl)amino-3,5-dihydrophenazine

Guidance literature:: With acetic acid; In 1,4-dioxane; at 110 ℃; Sealed tube;
DOI:10.3390/molecules19044380

Reference yield:

: 1-[2-(3,4-difluoroanilino)anilino]-3-fluoro-4,6-dinitrobenzene

: 1353740-16-5
5-(3,4-difluorophenyl)-3-cyclopropylimino-2-(2-methoxy-3-pyridyl)amino-3,5-dihydrophenazine

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / tetrahydrofuran / 31 h / Reflux

2: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 15 h / 20 °C / 2068.65 Torr

3: methanol / 18 h / 20 °C

4: acetic acid / 1,4-dioxane / 110 °C / Sealed tube

With palladium 10% on activated carbon; hydrogen; acetic acid; triethylamine; In tetrahydrofuran; 1,4-dioxane; methanol;
DOI:10.3390/molecules19044380

Reference yield:

: 1-[2-(3,4-difluoroanilino)anilino]-3-(2-methoxy-3-pyridyl)amino-4,6-dinitrobenzene

: 1353740-16-5
5-(3,4-difluorophenyl)-3-cyclopropylimino-2-(2-methoxy-3-pyridyl)amino-3,5-dihydrophenazine

Guidance literature:: Multi-step reaction with 3 steps

1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 15 h / 20 °C / 2068.65 Torr

2: methanol / 18 h / 20 °C

3: acetic acid / 1,4-dioxane / 110 °C / Sealed tube

With palladium 10% on activated carbon; hydrogen; acetic acid; In tetrahydrofuran; 1,4-dioxane; methanol;
DOI:10.3390/molecules19044380