N-tert-butoxycarbonyl-N-phenyl-O-(methoxycarbonyl)hydroxylamine

Base Information

• Chemical Name: N-tert-butoxycarbonyl-N-phenyl-O-(methoxycarbonyl)hydroxylamine
• CAS No.: 1095280-60-6
• Molecular Formula: C₁₃H₁₇NO₅
• Molecular Weight: 267.282
• Mol file: 1095280-60-6.mol

Synonyms:N-tert-butoxycarbonyl-N-phenyl-O-(methoxycarbonyl)hydroxylamine

Chemical Property of N-tert-butoxycarbonyl-N-phenyl-O-(methoxycarbonyl)hydroxylamine

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of N-tert-butoxycarbonyl-N-phenyl-O-(methoxycarbonyl)hydroxylamine

There total 1 articles about N-tert-butoxycarbonyl-N-phenyl-O-(methoxycarbonyl)hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

tert-butyl N-hydroxy-N-phenylcarbamate (58377-40-5) + methyl chloroformate (79-22-1) → N-tert-butoxycarbonyl-N-phenyl-O-(methoxycarbonyl)hydroxylamine (1095280-60-6)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1002/ejoc.200800672

Reference yield: 64.0%

N-tert-butoxycarbonyl-N-phenyl-O-(methoxycarbonyl)hydroxylamine (1095280-60-6) → 2-[(tert-butoxycarbonyl)amino]phenyl methyl carbonate (1095280-64-0)

Guidance literature:

With silver hexafluoroantimonate; cobalt(II) chloride; In 1,2-dichloro-ethane; at 30 ℃; for 6h; Inert atmosphere;

DOI:10.3762/bjoc.14.172

upstream raw materials:

tert-butyl N-hydroxy-N-phenylcarbamate

methyl chloroformate

Downstream raw materials:

2-[(tert-butoxycarbonyl)amino]phenyl methyl carbonate