58377-40-5

Upstream product

• 1538-75-6 2,2-dimethylpropanoic anhydride 
• 100-65-2 N-Phenylhydroxylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 98-95-3 nitrobenzene 
• 24608-52-4 tert-butyl chloroformate 
• 108-86-1 bromobenzene 
• 36016-38-3 tert-Butyl N-hydroxycarbamate 
• 1093102-65-8 N-tert-butoxycarbonyl-N-phenyl-O-(tert-butyldimethylsilyl)hydroxylamine 
• 1483-73-4 diphenyliodonium bromide 

Downstream Products

• 1095280-59-3 N-Boc-N-phenyl-O-Boc-hydroxylamine 
• 1095280-57-1 N-Boc-N-phenyl-O-benzoylhydroxylamine 
• 1095280-58-2 N-Boc-N-phenyl-O-(4-methoxybenzoyl)hydroxylamine 
• 1095280-56-0 N-Boc-N-phenyl-O-(4-nitrobenzoyl)hydroxylamine 
• 1093102-81-8 2-(Boc-amino)phenyl methanesulfonate 
• 1095280-60-6 N-tert-butoxycarbonyl-N-phenyl-O-(methoxycarbonyl)hydroxylamine 
• 1095280-67-3 toluene-4-sulfonic acid 2-tert-butoxycarbonylaminophenyl ester 
• 877172-23-1 tert-butyl phenyl-(1-phenylbut-3-enyloxy)carbamate 
• 1218786-38-9 N-Boc-2-(2',2',2'-trichloroacetylamino)-aniline 
• 371-40-4 4-fluoroaniline 
• 60144-53-8 N-(tert-butoxycarbonyl)-4-fluoroaniline 
• 214610-10-3 N-boc-2-oxyindole 
• 129822-50-0 tert-butyl 3-phenyl-1H-indole-1-carboxylate 
• 90924-33-7 Ethyl 2,1-benzisoxazole-3-carboxylate 

Relevant academic research and scientific papers

Regioselective installation of fluorosulfate (-OSO2F) functionality into aromatic C(sp2)-H bonds for the construction of: Para-amino-arylfluorosulfates

The construction of para-amino-arylfluorosulfates was achieved through installation of fluorosulfate (-OSO2F) functionality into aromatic C(sp2)-H bonds by the reaction of N-arylhydroxylamine with sulfuryl fluoride (SO2Fs

Hydroxamic Acids as Chemoselective (ortho-Amino)arylation Reagents via Sigmatropic Rearrangement

The use of readily available hydroxamic acids as reagents for the chemoselective (ortho-amino)arylation of amides is described. This reaction proceeds under metal-free, mild conditions, displays a very broad scope, and constitutes a direct approach for the metal-free attachment of aniline residues to carbonyl derivatives.

Palladium-catalyzed coupling of hydroxylamines with aryl bromides, chlorides, and iodides

The bis-pyrazole phosphine ligand BippyPhos is effective for the palladium-catalyzed cross-coupling of hydroxylamines with aryl bromides, chlorides, and iodides. Reactions proceed smoothly at 80 °C in toluene in the presence of Cs2CO3/sub

Facile procedure for the synthesis of N-aryl-N-hydroxy carbamates

An efficient one-pot procedure for the zinc-mediated reduction of nitroarenes in the presence of chloroformates leading to the corresponding N,O-bisprotected hydroxylamine is described. Reactions proceed smoothly under ambient conditions in THF-water mixt

Influence of hydroxylamine conformation on stereocontrol in Pd-catalyzed isoxazolidine-forming reactions

Palladium-catalyzed carboamination reactions between N-Boc-O-(but-3-enyl) hydroxylamine derivatives and aryl or alkenyl bromides afford cis-3,5- and trans-4,5-disubstituted isoxazolidines in good yield with up to >20:1 dr. The diastereoselectivity observe

Studies on the Preparation of N-Alkyl-O-phenylhydroxylamines

Several possible routes to the title compounds have been investigated.The reaction of N-hydroxycarbamates (1) with diphenyliodonium bromide gave, unexpectedly, N-hydroxy-N-phenylcarbamates (2), while N-methyl-N-hydroxycarbamates (6) gave 2-(N-methyl-N-alkoxycarbonylamino)phenols (7).Mechanistic aspects of the N-arylations and subsequent rearrangements are discussed.The desired N-alkyl-O-phenylhydroxylamines were obtained by the reduction of O-phenyloximes (15) with sodium cyanoborohydride.