2,2-DI(Acetoxymethyl)propionyl chloride

Base Information

Chemical Name:2,2-DI(Acetoxymethyl)propionyl chloride
CAS No.:17872-59-2
Molecular Formula:C9H13 Cl O5
Molecular Weight:236.652
Hs Code.:2915900090
DSSTox Substance ID:DTXSID30600294
Nikkaji Number:J759.297C
Wikidata:Q82496301
Mol file:17872-59-2.mol

Synonyms:17872-59-2;2,2-DI(ACETOXYMETHYL)PROPIONYL CHLORIDE;[2-(acetyloxymethyl)-3-chloro-2-methyl-3-oxopropyl] acetate;SCHEMBL7590854;DTXSID30600294;ZZNTYUTVZBEQIB-UHFFFAOYSA-N;AKOS030255547;DB-203814;2,2-bis-acetoxymethyl propionic acid chloride;2-(Chlorocarbonyl)-2-methylpropane-1,3-diyl diacetate;3-(Acetyloxy)-2-[(acetyloxy)methyl]-2-methylpropanoyl chloride

Suppliers and Price of 2,2-DI(Acetoxymethyl)propionyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2,2-DI(Acetoxymethyl)propionyl chloride

Chemical Property:

PSA：69.67000
LogP:0.88430
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:236.0451512
Heavy Atom Count:15
Complexity:256

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OCC(C)(COC(=O)C)C(=O)Cl

Technology Process of 2,2-DI(Acetoxymethyl)propionyl chloride

There total 3 articles about 2,2-DI(Acetoxymethyl)propionyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 17872-58-1
2,2-bis(acetoxymethyl)propionic acid

: 17872-59-2
2,2-bis(acetoxymethyl)propanoic acid chloride

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 25 ℃; for 2h;
DOI:10.1021/ja954171t

Reference yield:

: 4767-03-7
2,2-bis(hydroxymethyl)propionic acid

: 17872-59-2
2,2-bis(acetoxymethyl)propanoic acid chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / Et₃N, DMAP / CH₂Cl₂ / 0.5 h

2: 99 percent / (COCl)2, DMF / CH₂Cl₂ / 2 h / 25 °C

With dmap; oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1021/ja954171t