17872-58-1

Usage

Uses

Used in Pharmaceutical Industry:
2,2-BIS-(ACETOXYMETHYL)PROPIONIC ACID is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents due to its versatile reactivity and functional groups.
Used in Agrochemical Industry:
In the agrochemical sector, 2,2-BIS-(ACETOXYMETHYL)PROPIONIC ACID is utilized as a building block in the synthesis of agrochemicals, playing a crucial role in the production of pesticides and other agricultural chemicals to enhance crop protection and yield.
Used in Organic Synthesis:
2,2-BIS-(ACETOXYMETHYL)PROPIONIC ACID is employed as a chemical reagent in organic synthesis, facilitating the formation of more complex organic compounds through its participation in various chemical reactions.
Used as a Precursor for Complex Organic Compounds:
It also serves as a precursor in the synthesis of intricate organic compounds, enabling the creation of a wide range of chemical products for diverse applications across different industries.

Upstream product

• 4767-03-7 2,2-bis(hydroxymethyl)propionic acid 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 

Downstream Products

• 1303947-84-3 KNI-10858 
• 179388-74-0 3-(3-Acetoxy-2-acetoxymethyl-2-methyl-propionyloxy)-2-(3-acetoxy-2-acetoxymethyl-2-methyl-propionyloxymethyl)-2-methyl-propionic acid benzyl ester 
• 179388-87-5 C₅₈H₈₀O₃₀ 
• 17872-59-2 2,2-bis(acetoxymethyl)propanoic acid chloride 

Relevant academic research and scientific papers

Design and synthesis of several small-size HTLV-I protease inhibitors with different hydrophilicity profiles

The human T cell leukemia/lymphotropic virus type 1 (HTLV-I) is clinically associated with adult T cell leukemia/lymphoma, HTLV-I associated myelopathy/tropical spastic paraparesis, and a number of other chronic inflammatory diseases. To stop the replication of the virus, we developed highly potent tetrapeptidic HTLV-I protease inhibitors. In a recent X-ray crystallography study, several of our inhibitors could not form co-crystal complexes with the protease due to their high hydrophobicity. In the current study, we designed, synthesized and evaluated the HTLV-I protease inhibition potency of compounds with hydrophilic end-capping moieties with the aim of improving pharmaceutic and pharmacokinetic properties.

Synthesis, characterization, and 1H NMR self-diffusion studies of dendritic aliphatic polyesters based on 2,2-bis(hydroxymethyl)propionic acid and 1,1,1-tris(hydroxyphenyl)ethane

Dendritic aliphatic polyesters of one, two, three, and four generations (M(w): 906, 1856, 3754, and 7549 g/mol) were synthesized in the convergent fashion, using 2,2-bis(hydroxymethyl)propionic acid as building block and 1,1,1-tris(hydroxyphenyl)ethane as

Dye derived from a pyrazolotriazole

A method of retouching a dye image comprises selective removal with an aqueous acidic organic solvent solution, as described in the application, of a portion of a dye image from an exposed and processed photographic silver halide element comprising a support bearing a dye image from a dye-forming coupler and a primary amine photographic color developing agent, wherein the dye-forming coupler: (a) contains so ionizable group that is retained as part of a dye formed upon oxidative coupling, (b) has a structure such that the Log P of the coupler is greater than 4 and is derived from a four-equivalent coupler that has a Log P less than 8, and (c) has a coupling reactivity that enables formation of maximum image density of at least 0.6. The method comprises the step of contacting the dye image with an aqueous acidic organic solvent solution, as described in the application, for a time and at a temperature sufficient to selectively dissolve and remove a portion of the dye image from the photographic element. A new photographic element designed for such retouching comprises new pyrazolotriazole couplers as described in the application.