Dimethyl-carbamic acid (2R,3R,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester

Base Information

• Chemical Name: Dimethyl-carbamic acid (2R,3R,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester
• CAS No.: 156994-52-4
• Molecular Formula: C₁₃H₁₉N₃O₇
• Molecular Weight: 329.31
• Mol file: 156994-52-4.mol

Synonyms:Dimethyl-carbamic acid (2R,3R,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester

Chemical Property of Dimethyl-carbamic acid (2R,3R,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Dimethyl-carbamic acid (2R,3R,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester

There total 2 articles about Dimethyl-carbamic acid (2R,3R,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + 1-(β-D-xylofuranosyl)-thymine (52486-19-8,642082-80-2) → O-2,2'-cyclo-5-methyluridine (22423-26-3) + Dimethyl-carbamic acid (2R,3R,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester (156994-52-4)

Guidance literature:

With bis(phenyl) carbonate; sodium hydrogencarbonate; at 140 - 150 ℃; for 4h;

DOI:10.1039/c39940001255

Reference yield: 20.0%

1-(β-D-xylofuranosyl)-thymine (52486-19-8,642082-80-2) → O-2,2'-cyclo-5-methyluridine (22423-26-3) + Dimethyl-carbamic acid (2R,3R,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester (156994-52-4)

Guidance literature:

With bis(phenyl) carbonate; sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 140 - 150 ℃; for 4h;

DOI:10.1039/c39940001255

upstream raw materials:

N,N-dimethyl-formamide

1-(β-D-xylofuranosyl)-thymine