2-(3-Methoxyphenyl)-2-methylpropanenitrile

Base Information

Chemical Name:2-(3-Methoxyphenyl)-2-methylpropanenitrile
CAS No.:17653-93-9
Molecular Formula:C11H13 N O
Molecular Weight:175.23
Hs Code.:2926909090
DSSTox Substance ID:DTXSID30435967
Nikkaji Number:J1.259.842D
Wikidata:Q82251114
Mol file:17653-93-9.mol

Synonyms:2-(3-Methoxyphenyl)-2-methylpropanenitrile;17653-93-9;2-(3-methoxy-phenyl)-2-methyl-propionitrile;SCHEMBL1007659;DTXSID30435967;YMUMJIHZRRIBPK-UHFFFAOYSA-N;MFCD09414739;AKOS010514400;FS-2608;3-Methoxy-a,a-dimethylbenzeneacetonitrile;3-Methoxy-|A,|A-dimethylbenzeneacetonitrile;CS-0207551;alpha,alpha-Dimethyl-3-methoxybenzeneacetonitrile;EN300-1838213

Suppliers and Price of 2-(3-Methoxyphenyl)-2-methylpropanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-(3-Methoxyphenyl)-2-methylpropanenitrile 97%
1g
$ 304.00

Crysdot
2-(3-Methoxyphenyl)-2-methylpropanenitrile 95+%
5g
$ 405.00

Atlantic Research Chemicals
2-(3-Methoxyphenyl)-2-methylpropanenitrile 95%
250mgs:
$ 74.23

American Custom Chemicals Corporation
2-(3-METHOXYPHENYL)-2-METHYLPROPANENITRILE 95.00%
5MG
$ 504.02

Alichem
2-(3-Methoxyphenyl)-2-methylpropanenitrile
5g
$ 406.02

Alichem
2-(3-Methoxyphenyl)-2-methylpropanenitrile
25g
$ 1477.35

AK Scientific
2-(3-Methoxyphenyl)-2-methylpropanenitrile
5g
$ 584.00

Total 3 raw suppliers

Chemical Property of 2-(3-Methoxyphenyl)-2-methylpropanenitrile

Chemical Property:

PSA：33.02000
LogP:2.49638
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:175.099714038
Heavy Atom Count:13
Complexity:213

Purity/Quality:

99%, ^*data from raw suppliers

2-(3-Methoxyphenyl)-2-methylpropanenitrile 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C#N)C1=CC(=CC=C1)OC

Technology Process of 2-(3-Methoxyphenyl)-2-methylpropanenitrile

There total 11 articles about 2-(3-Methoxyphenyl)-2-methylpropanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 19924-43-7
3-methoxyphenylacetonitrile

: 74-88-4
methyl iodide

: 17653-93-9
2-(3'-Methoxyphenyl)-2-methylpropionitrile

Guidance literature:: 3-methoxyphenylacetonitrile; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 1.5h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; at 0 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.1c02460

Reference yield: 86.0%

: 12116-44-8
(η6-anisol)tricarbonyl chromium

: 50654-53-0
2-lithio-2-methylpropionitrile

: 17653-93-9
2-(3'-Methoxyphenyl)-2-methylpropionitrile

Guidance literature:: In tetrahydrofuran; reaction mixture is stirred at -60°C for 10 min;

Reference yield: 79.0%

: 25108-57-0
3-(1-methylethenyl)anisole

: 75-86-5
2-hydroxy-2-methylpropanenitrile

: 17653-93-9
2-(3'-Methoxyphenyl)-2-methylpropionitrile

Guidance literature:: With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; C₇₆H₆₀O₁₀P₂; In toluene; at 120 ℃; for 12h; Inert atmosphere; Glovebox;
DOI:10.1021/acs.orglett.9b04554