Caryophyllene

Base Information

• Chemical Name: Caryophyllene
• CAS No.: 17627-40-6
• Molecular Formula: C₁₅H₂₄
• Molecular Weight: 204.356
• Mol file: 17627-40-6.mol

Synonyms:Bicyclo[7.2.0]undec-4-ene,4,11,11-trimethyl-8-methylene-, (1R*,4E,9S*)-(?à)-; Bicyclo[7.2.0]undec-4-ene,4,11,11-trimethyl-8-methylene-, (1R,4E,9S)-rel- (9CI); (?à)-Caryophyllene

Chemical Property of Caryophyllene

Chemical Property:

• Vapor Pressure: 0.0128mmHg at 25°C
• Refractive Index: 1.494
• Boiling Point: 268.4°C at 760 mmHg
• Flash Point: 104.9°C
• PSA: 0.00000
• Density: 0.89g/cm³
• LogP: 4.72520

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Caryophyllene

There total 1 articles about Caryophyllene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-(1R,9S)-4,11,11-Trimethyl-8-methylene-bicyclo[7.2.0]undec-3-en-5-one (61824-50-8) → β-caryophyllene (87-44-5,118-65-0,10579-93-8,13877-93-5,17627-40-6,54061-81-3,61217-74-1,68832-35-9,89575-63-3) + caryophyllenol-I (19431-76-6,19431-77-7,32214-88-3,32214-89-4,34298-31-2,38284-08-1,73088-51-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Ambient temperature;

DOI:10.1016/S0040-4020(01)91590-X

Reference yield: 91.0%

(E)-β-caryophyllene (17627-40-6) + C6H4N2O4S3 (62925-73-9) → C21H28N2O4S3 (131877-88-8)

Guidance literature:

In diethyl ether; for 16h; Ambient temperature;

DOI:10.1016/S0040-4020(01)87924-2

Reference yield: 79.0%

β-caryophyllene (87-44-5,118-65-0,10579-93-8,13877-93-5,17627-40-6,54061-81-3,61217-74-1,68832-35-9,89575-63-3) → (1R,6R,10S)-5,12,12-Trimethyl-9-methylene-4-oxa-tricyclo[8.2.0.03,5]dodecan-6-ol (88514-14-1) + caryophyllenol-II (19431-76-6,19431-77-7,32214-88-3,32214-89-4,34298-31-2,38284-08-1,73088-51-4) + caryophyllene epoxide (1139-30-6,13877-94-6,17627-43-9,60594-22-1,60594-23-2,68832-36-0,103475-43-0,119818-36-9,119818-37-0)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; at 0 ℃; for 6h;

DOI:10.1016/S0040-4020(01)91590-X

upstream raw materials:

(Z)-(1R,9S)-4,11,11-Trimethyl-8-methylene-bicyclo[7.2.0]undec-3-en-5-one

Downstream raw materials:

C₂₁H₂₈N₂O₄S₃

caryophyllene nitrosite

dinitrocaryophyllene

4-Amino-N-((Z)-(1R,9S)-11,11-dimethyl-8-methylene-bicyclo[7.2.0]undec-4-en-4-ylmethyl)-benzenesulfonamide