(2R,3S)-tert-butyldimethylsilyloxymethyl-2-ethynyl-2-methyl-1-(2-nitrobenzenesulfonyl)-aziridine

Base Information

• Chemical Name: (2R,3S)-tert-butyldimethylsilyloxymethyl-2-ethynyl-2-methyl-1-(2-nitrobenzenesulfonyl)-aziridine
• CAS No.: 960595-73-7
• Molecular Formula: C₁₈H₂₆N₂O₅SSi
• Molecular Weight: 410.566

Synonyms:(2R,3S)-tert-butyldimethylsilyloxymethyl-2-ethynyl-2-methyl-1-(2-nitrobenzenesulfonyl)-aziridine

Chemical Property of (2R,3S)-tert-butyldimethylsilyloxymethyl-2-ethynyl-2-methyl-1-(2-nitrobenzenesulfonyl)-aziridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S)-tert-butyldimethylsilyloxymethyl-2-ethynyl-2-methyl-1-(2-nitrobenzenesulfonyl)-aziridine

There total 1 articles about (2R,3S)-tert-butyldimethylsilyloxymethyl-2-ethynyl-2-methyl-1-(2-nitrobenzenesulfonyl)-aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(2R,3S)-tert-butyldimethyl-[3-hydroxy-3-methyl-2-(2-nitrobenzenesulfonylamino)]-pent-4-ynoxysilane (960595-72-6) → (2R,3S)-tert-butyldimethylsilyloxymethyl-2-ethynyl-2-methyl-1-(2-nitrobenzenesulfonyl)-aziridine (960595-73-7)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/ja0758077

Reference yield: 96.0%

pyrrolidine (123-75-1) + (2R,3S)-tert-butyldimethylsilyloxymethyl-2-ethynyl-2-methyl-1-(2-nitrobenzenesulfonyl)-aziridine (960595-73-7) → N-[(2S,3S)-1-(tert-butyldimethylsilyloxy)-3-methyl-3-(pyrrolidin-1-yl)pent-4-yn-2-yl]-2-nitrobenzenesulfonamide (1243221-45-5)

Guidance literature:

In toluene; at 20 ℃; stereospecific reaction; Inert atmosphere;

DOI:10.1021/ol101584z

Reference yield: 60.0%

(2R,3S)-tert-butyldimethylsilyloxymethyl-2-ethynyl-2-methyl-1-(2-nitrobenzenesulfonyl)-aziridine (960595-73-7) + phenol (108-95-2,27073-41-2) → (2R,3S)-tert-butyldimethyl-[3-methyl-3-phenoxy-2-(2-nitrobenzenesulfonylamino)]pent-4-ynoxysilane (960595-88-4)

Guidance literature:

With 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; In toluene;

DOI:10.1021/ja0758077

upstream raw materials:

(2R,3S)-tert-butyldimethyl-[3-hydroxy-3-methyl-2-(2-nitrobenzenesulfonylamino)]-pent-4-ynoxysilane

Downstream raw materials:

(2R,3S)-tert-butyldimethyl-[3-methyl-3-phenoxy-2-(2-nitrobenzenesulfonylamino)]pent-4-ynoxysilane

N-[(2S,3S)-1-(tert-butyldimethylsilyloxy)-3-methyl-3-(pyrrolidin-1-yl)pent-4-yn-2-yl]-2-nitrobenzenesulfonamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 960595-73-7 (2R,3S)-tert-butyldimethylsilyloxymethyl-2-ethynyl-2-methyl-1-(2-nitrobenzenesulfonyl)-aziridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send