Beta-(2-pyridyl)-dl-alanine

Base Information

• Chemical Name: Beta-(2-pyridyl)-dl-alanine
• CAS No.: 17407-39-5
• Molecular Formula: C8H10N2O2
• Molecular Weight: 166.18
• Mol file: 17407-39-5.mol

Synonyms:2'-O-METHYLCYTIDINE ANHYDROUS

Chemical Property of Beta-(2-pyridyl)-dl-alanine

Chemical Property:

• Boiling Point: 322.4 °C at 760 mmHg
• Flash Point: 148.8 °C
• PSA: 76.21000
• Density: 1.271g/cm³
• LogP: 0.73630
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-3-(pyridin-2-yl)propionic acid AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Beta-(2-pyridyl)-dl-alanine

There total 12 articles about Beta-(2-pyridyl)-dl-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(S)-β-(2-pyridyl)-α-alanine-Ni-(S)-2-[N-(N-benzylpropyl)amino]benzophenone → (S)-2-amino-3-(pyridin-2-yl)propanoic acid (37535-51-6,17407-39-5,37535-52-7)

Guidance literature:

With hydrogenchloride; In methanol; water; at 80 ℃; for 1h; diastereoselective reaction;

DOI:10.1039/c3cc44717k

Reference yield: 98.0%

C21H24N2O4 → (S)-2-amino-3-(pyridin-2-yl)propanoic acid (37535-51-6,17407-39-5,37535-52-7)

Guidance literature:

With hydrogenchloride; In water; at 80 ℃; enantioselective reaction;

DOI:10.1039/c7sc03612d

Reference yield: 64.0%

Nα-acetyl-β-(2-pyridyl)-L-alanine (74164-26-4) → (S)-2-amino-3-(pyridin-2-yl)propanoic acid (37535-51-6,17407-39-5,37535-52-7)

Guidance literature:

With hydrogenchloride; for 4h; Heating;

upstream raw materials:

(E)-3-(2-pyridyl)acrylic acid

pyridine-2-carbaldehyde

(S)-2-amino-3-(pyridin-2-yl)propanoic acid

N^α-acetyl-β-(2-pyridyl)-L-alanine

Downstream raw materials:

N-(t-butoxycarbonyl)-3-(pyridin-2-yl)-DL-alanine

D,L-β-(2-pyridyl)-α-alanine

2-(4-Bromo-benzylamino)-3-pyridin-2-yl-propionic acid

2-(4-Chloro-benzylamino)-3-pyridin-2-yl-propionic acid

Refernces

• 1、 Lovelock, Sarah L.,Lloyd, Richard C.,Turner, Nicholas J.. "Phenylalanine ammonia lyase catalyzed synthesis of amino acids by an MIO-cofactor independent pathway". . p. 4652 - 4656. Retrieved 2014/05/20.
• 2、 -. "Fused purine derivatives". . . Retrieved 2008/06/13.