2-Bromo-1-(5-bromofuran-2-YL)ethanone

Base Information

• Chemical Name: 2-Bromo-1-(5-bromofuran-2-YL)ethanone
• CAS No.: 17357-32-3
• Molecular Formula: C6H4 Br2 O2
• Molecular Weight: 267.905
• Hs Code.: 2932190090
• DSSTox Substance ID: DTXSID90501718
• Mol file: 17357-32-3.mol

Synonyms:17357-32-3;2-BROMO-1-(5-BROMOFURAN-2-YL)ETHANONE;Ethanone, 2-bromo-1-(5-bromo-2-furanyl)-;2-BROMO-1-(5-BROMOFURAN-2-YL)-ETHANONE;2-Bromo-1-(5-bromofuran-2-yl)ethan-1-one;5-bromo-2-bromoacetylfuran;SCHEMBL3301544;DTXSID90501718;WTFKIDCAQZPAHP-UHFFFAOYSA-N;3,4-Diaminothiophenedihydrochloride;MFCD07785843;AKOS017558911;AB42923;CS-0215741;C90418;EN300-2967219

Chemical Property of 2-Bromo-1-(5-bromofuran-2-YL)ethanone

Chemical Property:

• PSA: 30.21000
• LogP: 2.61970
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 267.85576
• Heavy Atom Count: 10
• Complexity: 138

Purity/Quality:

98%min ^*data from raw suppliers

2-BROMO-1-(5-BROMO-FURAN-2-YL)ETHANONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(OC(=C1)Br)C(=O)CBr

Technology Process of 2-Bromo-1-(5-bromofuran-2-YL)ethanone

There total 4 articles about 2-Bromo-1-(5-bromofuran-2-YL)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1-(5-bromofuran-2-yl)ethanone (3199-50-6) → 2-bromo-1-(5-bromofuran-2-yl)ethanone (17357-32-3)

Guidance literature:

With bromine; In 1,4-dioxane; diethyl ether; at 0 - 5 ℃;

DOI:10.1021/jm0400092

Reference yield:

1-(2-furyl)-1-ethanone (1192-62-7,80145-44-4) → 1-(2-furyl)-2-bromoethanone (15109-94-1) + 2-bromo-1-(5-bromofuran-2-yl)ethanone (17357-32-3)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; for 2h; Heating;

DOI:10.1002/ardp.19973300908

Reference yield:

5-bromofuran-2-carbonyl chloride (26726-16-9) → 2-bromo-1-(5-bromofuran-2-yl)ethanone (17357-32-3)

Guidance literature:

5-bromofuran-2-carbonyl chloride; With diazomethyl-trimethyl-silane; In tetrahydrofuran; dichloromethane; at 0 ℃; for 2.5h;

With hydrogen bromide; In tetrahydrofuran; dichloromethane; water; at 0 ℃; for 0.5h;

upstream raw materials:

1-(5-bromofuran-2-yl)ethanone

1-(2-furyl)-1-ethanone

5-bromofuran-2-carbonyl chloride

Downstream raw materials:

5-bromo-furan-2-carboxylic acid

2-methyl-4-(5'-nitro-2'-furyl)thiazole

C₁₂H₈Cl₂O₂

1-methyl-2-phenyl-5-(5'-bromo-2'-furyl)imidazole