2-<1-hydroxy-1-methyl>-4-methylthiazole

Base Information

Chemical Name:2-<1-hydroxy-1-methyl>-4-methylthiazole
CAS No.:129422-61-3
Molecular Formula:C₁₂H₁₀F₃NOS
Molecular Weight:273.279
Hs Code.:

2-<1-hydroxy-1-<p-(trifluoromethyl)phenyl>methyl>-4-methylthiazole

Synonyms:2-<1-hydroxy-1-methyl>-4-methylthiazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-<1-hydroxy-1-methyl>-4-methylthiazole

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Technology Process of 2-<1-hydroxy-1-methyl>-4-methylthiazole

There total 1 articles about 2-<1-hydroxy-1-methyl>-4-methylthiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 693-95-8
4-Methylthiazole

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 129422-61-3
2-<1-hydroxy-1-methyl>-4-methylthiazole

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction; 1.) THF, 30 min, 2.) 2 h;

Reference yield:

: 129422-61-3
2-<1-hydroxy-1-methyl>-4-methylthiazole

: 2-<1-methoxy-1-methyl>-N,4-dimethylthiazolium fluoroborate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) THF, 30 min, 2.) 2 h

2: 94 percent / CH₂Cl₂ / 72 h

With sodium hydride; In dichloromethane;