(R)-N₅-[amino(nitroimino)methyl]-N₂-(diphenylacetyl)-N-[[4-(hydroxymethyl)phenyl]methyl]-ornithinamide

Base Information

• Chemical Name: (R)-N₅-[amino(nitroimino)methyl]-N₂-(diphenylacetyl)-N-[[4-(hydroxymethyl)phenyl]methyl]-ornithinamide
• CAS No.: 164645-85-6
• Molecular Formula: C₂₈H₃₂N₆O₅
• Molecular Weight: 532.599

Synonyms:(R)-N₅-[amino(nitroimino)methyl]-N₂-(diphenylacetyl)-N-[[4-(hydroxymethyl)phenyl]methyl]-ornithinamide

Chemical Property of (R)-N₅-[amino(nitroimino)methyl]-N₂-(diphenylacetyl)-N-[[4-(hydroxymethyl)phenyl]methyl]-ornithinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of (R)-N₅-[amino(nitroimino)methyl]-N₂-(diphenylacetyl)-N-[[4-(hydroxymethyl)phenyl]methyl]-ornithinamide

There total 2 articles about (R)-N₅-[amino(nitroimino)methyl]-N₂-(diphenylacetyl)-N-[[4-(hydroxymethyl)phenyl]methyl]-ornithinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

(R)-N5-[amino-(nitroimino)-methyl]-N2-(diphenylacetyl)ornithine (159013-58-8) + 4-hydroxymethyl-benzylamine (39895-56-2) + isobutyl chloroformate (543-27-1) → (R)-N5-[amino(nitroimino)methyl]-N2-(diphenylacetyl)-N-[[4-(hydroxymethyl)phenyl]methyl]-ornithinamide (164645-85-6)

Guidance literature:

Reference yield:

diphenylacetic acid chloride (1871-76-7) → (R)-N5-[amino(nitroimino)methyl]-N2-(diphenylacetyl)-N-[[4-(hydroxymethyl)phenyl]methyl]-ornithinamide (164645-85-6)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride; sodium hydroxide / tetrahydrofuran; water; ethyl acetate

With hydrogenchloride; sodium hydroxide; In tetrahydrofuran; water; ethyl acetate;

Reference yield:

(R)-N5-[amino(nitroimino)methyl]-N2-(diphenylacetyl)-N-[[4-(hydroxymethyl)phenyl]methyl]-ornithinamide (164645-85-6) + phenyl chloroformate (1885-14-9) → (R)-N5-[Amino(nitroimino)methyl]-N2-(diphenylacetyl)-N-[[4-(phenoxycarbonyloxymethyl)phenyl]methyl]-ornithinamide (191869-36-0)

Guidance literature:

In pyridine; water;

upstream raw materials:

(R)-N₅-[amino-(nitroimino)-methyl]-N₂-(diphenylacetyl)ornithine

4-hydroxymethyl-benzylamine

isobutyl chloroformate

diphenylacetic acid chloride

Downstream raw materials:

(R)-N₅-[Amino(nitroimino)methyl]-N₂-(diphenylacetyl)-N-[[4-(phenoxycarbonyloxymethyl)phenyl]methyl]-ornithinamide

(R)-N-[[4-(Aminocarbonyloxymethyl)phenyl]methyl]-N₅-[amino(nitroimino)methyl]-N₂-(diphenylacetyl)-ornithinamide

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