(3-Fluorophenyl) magnesium bromide

Base Information

Chemical Name:(3-Fluorophenyl) magnesium bromide
CAS No.:17318-03-5
Molecular Formula:C6H4BrFMg
Molecular Weight:199.305
Hs Code.:29319090
DSSTox Substance ID:DTXSID90380808
Mol file:17318-03-5.mol

Synonyms:(3-fluorophenyl) magnesium bromide;DTXSID90380808

Suppliers and Price of (3-Fluorophenyl) magnesium bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-FluorophenylmagnesiumBromide,1.0MsolutioninTHF,J&KSeal
100mg
$ 60.00

Sigma-Aldrich
3-Fluorophenylmagnesium bromide solution 1.0 M in THF
4x25ml
$ 177.00

Sigma-Aldrich
3-Fluorophenylmagnesium bromide solution 1.0 M in THF
100ml
$ 171.00

Sigma-Aldrich
3-Fluorophenylmagnesium bromide solution 0.5 M in THF
50ml
$ 154.00

Rieke Metals
3-Fluorophenylmagnesiumbromide
50mL
$ 204.00

Rieke Metals
3-Fluorophenylmagnesiumbromide
50mL
$ 204.00

Rieke Metals
3-Fluorophenylmagnesiumbromide
50mL
$ 395.00

Rieke Metals
3-Fluorophenylmagnesiumbromide
100mL
$ 356.00

Rieke Metals
3-Fluorophenylmagnesiumbromide
100mL
$ 356.00

Matrix Scientific
3-Fluorophenylmagnesiumbromide 1.0MinTHF97%
100ml
$ 256.00

Total 34 raw suppliers

Chemical Property of (3-Fluorophenyl) magnesium bromide

Chemical Property:

Boiling Point:65 °C
Flash Point:<1 °F
PSA：0.00000
Density:1.024 g/mL at 25 °C
LogP:2.47150
Storage Temp.:2-8°C
Sensitive.:Air & Moisture Sensitive
Water Solubility.:It reacts violently with water.
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:197.93308
Heavy Atom Count:9
Complexity:140

Purity/Quality:

97% ^*data from raw suppliers

3-FluorophenylmagnesiumBromide,1.0MsolutioninTHF,J&KSeal ^*data from reagent suppliers

Safty Information:

Pictogram(s): F;C
Hazard Codes:F,C
Statements: 11-14-19-34-22-40-37
Safety Statements: 16-26-33-36/37/39-45-7/8-43

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C[C-]=CC(=C1)F.[Mg+2].[Br-]
Uses 3-Fluorophenylmagnesium bromide is used as a Grignard reagent in greener solvent, 2-methyltetrahydrofuran (2-MeTHF). 3-Fluorophenylmagnesium bromide is a Grignard reagent that can be used in:The preparation of 4-substituted quinazolines by reacting with 2-methylaminobenzonitriles.The synthesis of radiolabeled TrkB/C-targeting kinase inhibitor for positron emission tomography (PET) imaging applications.Cu-catalyzed carbometalation of substituted cyclopropenes.

Technology Process of (3-Fluorophenyl) magnesium bromide

There total 2 articles about (3-Fluorophenyl) magnesium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: ethyl acetate n-hexane

: 1073-06-9
3-fluorobromobenzene

: 75716-82-4
imidazol-1-yl-oxo-acetic acid ethyl ester

: 17318-03-5
bromo(3-fluorophenyl)magnesium

: 110193-59-4
ethyl 2-(3-fluorophenyl)-2-oxoacetate

Guidance literature:

Reference yield:

: 1073-06-9
3-fluorobromobenzene

: 17318-03-5
bromo(3-fluorophenyl)magnesium

Guidance literature:: With isopropylmagnesium bromide; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1016/S0040-4039(99)01404-5

Reference yield: 100.0%

: 17318-03-5
bromo(3-fluorophenyl)magnesium

: 147767-51-9,126645-52-1
4-benzyl-2-cyanomorpholine

: 664361-11-9
(+/-)-(4-benzylmorpholin-2-yl)-(3-fluorophenyl)methanone

Guidance literature:: bromo(3-fluorophenyl)magnesium; 4-benzyl-2-cyanomorpholine; In tetrahydrofuran; diethyl ether; at -10 - 20 ℃; for 2h;

With hydrogenchloride; water; In tetrahydrofuran; diethyl ether; at 0 ℃; for 0.5h;