75716-82-4Relevant articles and documents
Asymmetric synthesis of an antagonist of neurokinin receptors: SSR 241586
Metro, Thomas-Xavier,Cochi, Anne,Gomez Pardo, Domingo,Cossy, Janine
scheme or table, p. 2594 - 2602 (2011/06/20)
SSR 241586 is a 2,2-disubstituted morpholine, developed by Sanofi-Aventis, which is active in the treatment of schizophrenia and irritable bowel syndrome (IBS). Different strategies have been studied to synthesize this molecule and among the strategies an
Enantioselective synthesis of SSR 241586 by using an organo-catalyzed Henry reaction
Cochi, Anne,Metro, Thomas-Xavier,Pardo, Domingo Gomez,Cossy, Janine
supporting information; experimental part, p. 3693 - 3695 (2010/10/20)
An organo-catalyzed Henry reaction, applied to an α-keto ester, has allowed the enantioselective synthesis of SSR 241586, a 2,2-disubstituted morpholine active in the treatment of schizophrenia and irritable bowel syndrome (IBS).
FUNGICIDAL PYRIDAZINES
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Page/Page column 51, (2010/04/27)
Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein R1, R2, R3, R4, X, Y and m are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.