Ethyl 1-methylpyrrolidine-2-carboxylate

Base Information

Chemical Name:Ethyl 1-methylpyrrolidine-2-carboxylate
CAS No.:30727-23-2
Molecular Formula:C₈H₁₅NO₂
Molecular Weight:157.213
Hs Code.:
NSC Number:45493
DSSTox Substance ID:DTXSID20286405
Mol file:30727-23-2.mol

Synonyms:Proline, 1-methyl-, ethyl ester (9CI);D-Proline, 1-methyl-, ethyl ester (9CI);90243-87-1;42002-99-3;NSC45493;ethyl 1-methylpyrrolidine-2-carboxylate;2-Carbethoxy-N-methylpyrrolidine;SCHEMBL11490823;DTXSID20286405;NSC-45493;AKOS011304126;Ethyl 1-methyl-2-pyrrolidinecarboxylate #

Suppliers and Price of Ethyl 1-methylpyrrolidine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of Ethyl 1-methylpyrrolidine-2-carboxylate

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:157.110278721
Heavy Atom Count:11
Complexity:147

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1CCCN1C

Technology Process of Ethyl 1-methylpyrrolidine-2-carboxylate

There total 6 articles about Ethyl 1-methylpyrrolidine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 172223-88-0
C₂₀H₂₆NO₄P

: 30727-23-2,42002-99-3,936-14-1
1-methyl-DL-prolin-ethyl ester

Guidance literature:: With lithium diisopropyl amide;
DOI:10.1016/0040-4039(95)01567-2

Reference yield:

: 14660-52-7
ethyl 5-bromovalerate

: 30727-23-2,42002-99-3,936-14-1
1-methyl-DL-prolin-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N, Et₄NI / hexamethylphosphoric acid triamide

2: Et₃N

3: 75 percent / LDA

With tetraethylammonium iodide; triethylamine; lithium diisopropyl amide; In N,N,N,N,N,N-hexamethylphosphoric triamide;
DOI:10.1016/0040-4039(95)01567-2

Reference yield:

: 172223-81-3
5-(Hydroxy-methyl-amino)-pentanoic acid ethyl ester

: 30727-23-2,42002-99-3,936-14-1
1-methyl-DL-prolin-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N

2: 75 percent / LDA

With triethylamine; lithium diisopropyl amide;
DOI:10.1016/0040-4039(95)01567-2