Technology Process of 5-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)benzofuran-2-carbaldehyde
There total 5 articles about 5-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)benzofuran-2-carbaldehyde which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
manganese(IV) oxide;
In
1,4-dioxane;
for 1h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dimethyl sulfoxide / 0.33 h / 40 °C / Inert atmosphere
1.2: 20 - 120 °C / Inert atmosphere
2.1: manganese(IV) oxide / 1,4-dioxane / 1 h / Reflux
With
manganese(IV) oxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
1,4-dioxane; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: ammonium hydroxide; iodine; potassium iodide / water / 6 h
2.1: copper(I) oxide; pyridine / 0.75 h / Inert atmosphere; Reflux
3.1: hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine / ethanol / 3 h / 71 °C
4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dimethyl sulfoxide / 0.33 h / 40 °C / Inert atmosphere
4.2: 20 - 120 °C / Inert atmosphere
5.1: manganese(IV) oxide / 1,4-dioxane / 1 h / Reflux
With
pyridine; copper(I) oxide; manganese(IV) oxide; ammonium hydroxide; hydroxylamine hydrochloride; iodine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; potassium iodide;
In
1,4-dioxane; ethanol; water; dimethyl sulfoxide;
