4-[1-(Benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester

Base Information

Chemical Name:4-[1-(Benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester
CAS No.:1380646-06-9
Molecular Formula:C₂₅H₂₁FN₂O₄
Molecular Weight:432.451
Hs Code.:

Synonyms:4-[1-(Benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester

Suppliers and Price of 4-[1-(Benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[1-(Benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[1-(Benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester

There total 2 articles about 4-[1-(Benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 4570-41-6
1,3-benzoxazol-2-amine

: 1380646-60-5
4-[1-carboxy-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester

: 1380646-06-9
4-[1-(Benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;

Reference yield:

: ethyl 4-(2-tert-butoxy-2-oxo-ethyl)benzoate

: 1380646-06-9
4-[1-(Benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.67 h / 0 - 20 °C

1.2: 1 h / 20 °C

2.1: trifluoroacetic acid / dichloromethane / 5 h / 20 °C

3.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

With dmap; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide; mineral oil;

Reference yield: 91.0%

: 1380646-06-9
4-[1-(Benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester

: 1380646-61-6
4-[1-(benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid

Guidance literature:: 4-[1-(Benzooxazol-2-ylcarbamoyl)-2-(4-fluoro-phenyl)-ethyl]-benzoic acid ethyl ester; With water; potassium hydroxide; In ethanol; at 20 ℃; for 4h;

With hydrogenchloride; In methanol; dichloromethane; water;