DL-2,3-bis[(3,4,5-trimethoxybenzoyl)amino]propionic acid methyl ester

Base Information

• Chemical Name: DL-2,3-bis[(3,4,5-trimethoxybenzoyl)amino]propionic acid methyl ester
• CAS No.: 897932-28-4
• Molecular Formula: C₂₄H₃₀N₂O₁₀
• Molecular Weight: 506.51
• Mol file: 897932-28-4.mol

Synonyms:DL-2,3-bis[(3,4,5-trimethoxybenzoyl)amino]propionic acid methyl ester

Chemical Property of DL-2,3-bis[(3,4,5-trimethoxybenzoyl)amino]propionic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of DL-2,3-bis[(3,4,5-trimethoxybenzoyl)amino]propionic acid methyl ester

There total 1 articles about DL-2,3-bis[(3,4,5-trimethoxybenzoyl)amino]propionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2,3-diaminopropanoate dihydrochloride (6059-44-5,106973-48-2,147857-43-0) + Eudesmic acid (118-41-2) → DL-2,3-bis[(3,4,5-trimethoxybenzoyl)amino]propionic acid methyl ester (897932-28-4)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 0 - 60 ℃;

DOI:10.1016/j.bmc.2006.02.030

Reference yield: 99.0%

DL-2,3-bis[(3,4,5-trimethoxybenzoyl)amino]propionic acid methyl ester (897932-28-4) → DL-2,3-bis[(3,4,5-trimethoxybenzoyl)amino]propionic acid

Guidance literature:

With lithium hydroxide; In methanol; dichloromethane; water; for 8h;

DOI:10.1016/j.bmc.2006.02.030

Reference yield:

DL-2,3-bis[(3,4,5-trimethoxybenzoyl)amino]propionic acid methyl ester (897932-28-4) → 2,3-bis-(3,4,5-trimethoxy-benzoylamino)-propionic acid 2,2-dimethyl-propionyloxymethyl ester

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / lithium hydroxide / CH₂Cl₂; methanol; H₂O / 8 h

2: triethylamine / dimethylformamide / 3 h / 70 °C

With lithium hydroxide; triethylamine; In methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2006.02.030

upstream raw materials:

methyl 2,3-diaminopropanoate dihydrochloride

Eudesmic acid