(2S,3R,5R,7S,8R)-2-acetoxymethyl-3,7-bis(benzoyloxy)-5-methyloxocan-2,8-dimethanol

Base Information

Chemical Name:(2S,3R,5R,7S,8R)-2-acetoxymethyl-3,7-bis(benzoyloxy)-5-methyloxocan-2,8-dimethanol
CAS No.:193279-66-2
Molecular Formula:C₂₆H₃₀O₈
Molecular Weight:470.519
Hs Code.:

Synonyms:(2S,3R,5R,7S,8R)-2-acetoxymethyl-3,7-bis(benzoyloxy)-5-methyloxocan-2,8-dimethanol

Suppliers and Price of (2S,3R,5R,7S,8R)-2-acetoxymethyl-3,7-bis(benzoyloxy)-5-methyloxocan-2,8-dimethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,5R,7S,8R)-2-acetoxymethyl-3,7-bis(benzoyloxy)-5-methyloxocan-2,8-dimethanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,5R,7S,8R)-2-acetoxymethyl-3,7-bis(benzoyloxy)-5-methyloxocan-2,8-dimethanol

There total 4 articles about (2S,3R,5R,7S,8R)-2-acetoxymethyl-3,7-bis(benzoyloxy)-5-methyloxocan-2,8-dimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-05-4,9003-20-7
vinyl acetate

: (2S*,3R*,5R*,7S*,8R*)-3,7-bis(benzoyloxy)-5-methyloxocan-2,8-dimethanol

: 193279-66-2
(2S,3R,5R,7S,8R)-2-acetoxymethyl-3,7-bis(benzoyloxy)-5-methyloxocan-2,8-dimethanol

: C₂₆H₃₀O₈

Guidance literature:: With lipase AK; In acetonitrile; at 30 ℃; for 120h; Title compound not separated from byproducts;
DOI:10.1016/S0040-4020(99)00370-1

Reference yield:

: 98-88-4
benzoyl chloride

: 193279-66-2
(2S,3R,5R,7S,8R)-2-acetoxymethyl-3,7-bis(benzoyloxy)-5-methyloxocan-2,8-dimethanol

Guidance literature:: Multi-step reaction with 3 steps

1: DMAP / pyridine / 17 h / 20 °C

2: 76 percent / HF / acetonitrile / 3.5 h / 20 °C

3: lipase AK / acetonitrile / 120 h / 30 °C

With dmap; lipase AK; hydrogen fluoride; In pyridine; acetonitrile; 1: Acylation / 2: Hydrolysis / 3: Acetylation;
DOI:10.1016/S0040-4020(99)00370-1

Reference yield:

: (2S*,3R*,5R*,7S*,8R*)-5-methyl-2,8-bis(triisopropylsilyloxymethyl)oxocan-3,7-diol

: 193279-66-2
(2S,3R,5R,7S,8R)-2-acetoxymethyl-3,7-bis(benzoyloxy)-5-methyloxocan-2,8-dimethanol

Guidance literature:: Multi-step reaction with 3 steps

1: DMAP / pyridine / 17 h / 20 °C

2: 76 percent / HF / acetonitrile / 3.5 h / 20 °C

3: lipase AK / acetonitrile / 120 h / 30 °C

With dmap; lipase AK; hydrogen fluoride; In pyridine; acetonitrile; 1: Acylation / 2: Hydrolysis / 3: Acetylation;
DOI:10.1016/S0040-4020(99)00370-1