(1,2-Diethoxy-2-oxoethyl)triphenylphosphonium chloride

Base Information

• Chemical Name: (1,2-Diethoxy-2-oxoethyl)triphenylphosphonium chloride
• CAS No.: 16847-90-8
• Molecular Formula: C24H26 O3 P . Cl
• Molecular Weight: 428.895
• Hs Code.: 2931900090
• European Community (EC) Number: 605-517-0
• Mol file: 16847-90-8.mol

Synonyms:16847-90-8;(1,2-diethoxy-2-oxoethyl)triphenylphosphonium chloride;ETHOXY-ETHOXYCARBONYL-METHYLTRIPHENYLPHOSPHONIUM CHLORIDE;(1,2-diethoxy-2-oxoethyl)-triphenylphosphanium;chloride;Phosphonium, (1,2-diethoxy-2-oxoethyl)triphenyl-, chloride (1:1);SCHEMBL1549258;MMJCDOWKUCLEQX-UHFFFAOYSA-M;MFCD00159378;AKOS017345090;(1,2-diethoxy-2-oxoethyl)triphenylphosphoniumchloride;(1,2-diethoxy-2-oxoethyl)(triphenyl)phosphonium chloride;(1,2-diethoxy-2-oxoethyl)triphenyl phosphonium chloride;(1,2-diethoxy-2-oxoethyl) (triphenyl)phosphonium chloride;(1,2-diethoxy-2-oxoethyl)(triphenyl) phosphonium chloride;(ethoxy-ethoxycarbonylmethyl)-triphenylphosphonium chloride;[(Ethoxy-ethoxycarbonyl)methyl]triphenylphosphonium chloride;(ethoxy-ethoxy-carbonyl-methyl)-triphenyl-phosphonium chloride;(ethoxy-ethoxycarbonyl-methyl)-triphenyl-phosphonium chloride

Chemical Property of (1,2-Diethoxy-2-oxoethyl)triphenylphosphonium chloride

Chemical Property:

• PSA: 49.12000
• LogP: 0.91020
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 428.1308094
• Heavy Atom Count: 29
• Complexity: 417

Purity/Quality:

98%Min ^*data from raw suppliers

ETHOXY-ETHOXYCARBONYL-METHYLTRIPHENYLPHOSPHONIUM CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(C(=O)OCC)[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Cl-]

Technology Process of (1,2-Diethoxy-2-oxoethyl)triphenylphosphonium chloride

There total 3 articles about (1,2-Diethoxy-2-oxoethyl)triphenylphosphonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

ethyl 2-chloro-2-ethoxyacetate (34006-60-5) + triphenylphosphine (603-35-0) → (1,2-diethoxy-2-oxoethyl)triphenylphosphonium chloride (16847-90-8)

Guidance literature:

In chloroform; at 25 ℃; for 25h;

DOI:10.1016/S0040-4020(01)90482-X

Reference yield:

Ethyl diethoxyacetate (6065-82-3) → (1,2-diethoxy-2-oxoethyl)triphenylphosphonium chloride (16847-90-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / acetyl chloride / iodine / 1 h / 50 °C

2: 84 percent / CHCl₃ / 25 h / 25 °C

With acetyl chloride; iodine; In chloroform;

DOI:10.1016/S0040-4020(01)90482-X

Reference yield:

→ (1,2-diethoxy-2-oxoethyl)triphenylphosphonium chloride (16847-90-8)

Guidance literature:

upstream raw materials:

ethyl 2-chloro-2-ethoxyacetate

triphenylphosphine

Ethyl diethoxyacetate

Downstream raw materials:

(E)-2-ethoxy-3-phenylacrylic acid ethyl ester

(Z)-2-ethoxy-3-phenylacrylic acid ethyl ester

(rac)-2-ethoxy-3-(4-hydroxy-2-methyl-phenyl)-propionic acid ethyl ester

(Z)-3-(4-{3-[4-(butane-1-sulfonyloxy)-3-methoxy-phenyl]-propyl}-3-butoxy-phenyl)-2-ethoxy-ethyl acrylate