8-HYDROXY-6-NITROQUINOLINE

Base Information

• Chemical Name: 8-HYDROXY-6-NITROQUINOLINE
• CAS No.: 16727-28-9
• Molecular Formula: C₉H₆N₂O₃
• Molecular Weight: 190.158
• Hs Code.: 2933499090
• Mol file: 16727-28-9.mol

Synonyms:6-Nitro-8-quinolinol;8-Hydroxy-6-nitroquinoline

Chemical Property of 8-HYDROXY-6-NITROQUINOLINE

Chemical Property:

• Vapor Pressure: 3.67E-07mmHg at 25°C
• Refractive Index: 1.728
• Boiling Point: 405.7°Cat760mmHg
• Flash Point: 199.2°C
• PSA: 78.94000
• Density: 1.496g/cm³
• LogP: 2.37180
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

6-nitroquinolin-8-ol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-HYDROXY-6-NITROQUINOLINE

There total 3 articles about 8-HYDROXY-6-NITROQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C9H5BF3N2O2(1-)*K(1+) → 8-hydroxy-6-nitroquinoline (16727-28-9)

Guidance literature:

With potassium carbonate; benzenesufonyl hydrazide; at 150 ℃; for 12h;

Reference yield: 68.0%

8-methoxy-6-nitroquinoline (80912-11-4) → 8-hydroxy-6-nitroquinoline (16727-28-9)

Guidance literature:

With hydrogen bromide; In trifluoroacetic acid; for 3h; Heating;

Reference yield:

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) + 5-Nitro-2-aminophenol (121-88-0) → 8-hydroxy-6-nitroquinoline (16727-28-9)

Guidance literature:

With sulfuric acid; water; orthoarsenic acid;

DOI:10.1002/ardp.19582910405

upstream raw materials:

glycerol

5-Nitro-2-aminophenol

8-methoxy-6-nitroquinoline

Downstream raw materials:

6-amino-8-hydroxyquinoline