4-Chlorophenylselenol

Base Information

• Chemical Name: 4-Chlorophenylselenol
• CAS No.: 16645-10-6
• Molecular Formula: C6H5 Cl Se
• Molecular Weight: 191.519
• Hs Code.: 2906299090
• DSSTox Substance ID: DTXSID70422538
• Nikkaji Number: J1.881.487K
• Wikidata: Q82234487
• Mol file: 16645-10-6.mol

Synonyms:4-Chlorophenylselenol;16645-10-6;4-Chlorobenzeneselenol #;1-chloro-4-$l^{1};SCHEMBL9464469;[(4-Chlorophenyl)seleno]radical;DTXSID70422538;AKOS006274082

Chemical Property of 4-Chlorophenylselenol

Chemical Property:

• Melting Point: 55 °C
• Boiling Point: 102-103 °C(Press: 16 Torr)
• PKA: 3.73±0.70(Predicted)
• PSA: 0.00000
• LogP: 1.05020
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 190.91667
• Heavy Atom Count: 8
• Complexity: 66.9

Purity/Quality:

99%min ^*data from raw suppliers

4-CHLOROPHENYLSELENOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1Cl)[Se]

Technology Process of 4-Chlorophenylselenol

There total 8 articles about 4-Chlorophenylselenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloro-phenyl magnesium (1+); bromide → bis(p-chlorophenyl) diselenide (20541-49-5) + p-chloroselenophenol (16645-10-6)

Guidance literature:

Reference yield:

bis(p-chlorophenyl) diselenide (20541-49-5) → p-chloroselenophenol (16645-10-6)

Guidance literature:

With water; hypophosphorous acid; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.tetlet.2013.12.086

Reference yield:

bromochlorobenzene (106-39-8) → p-chloroselenophenol (16645-10-6)

Guidance literature:

With selenium; magnesium; Multistep reaction; 1) Et₂O, 2) Et₂O, 20 min;

DOI:10.1021/jo00171a002

upstream raw materials:

1-chloro-4-selenocyanatobenzene

bromochlorobenzene

bis(p-chlorophenyl) diselenide

Downstream raw materials:

4-chlorobenzeneseleninic acid

β-(p-chlorophenylseleno)acrylamide

3-(4-Chloro-phenylselanyl)-1,2,4,5-tetramethyl-benzene

1-(4-Chloro-phenylselanyl)-2,3,4,5,6-pentamethyl-benzene

Refernces

• 1、 Wang, Xin-Yu,Zhong, Yuan-Fang,Mo, Zu-Yu,Wu, Shi-Hong,Xu, Yan-Li,Tang, Hai-Tao,Pan, Ying-Ming. "Synthesis of Seleno Oxindoles via Electrochemical Cyclization of N-arylacrylamides with Diorganyl Diselenides". supporting information. p. 208 - 214. Retrieved 2020/12/04.
• 2、 Balaguez, Renata A.,Ricordi, Vanessa Gentil,Freitas, Camilo S.,Perin, Gelson,Schumacher, Ricardo F.,Alves, Diego. "Simple and catalyst-free method for the synthesis of diaryl selenides by reactions of arylselenols and arenediazonium salts". supporting information. p. 1057 - 1061. Retrieved 2015/02/19.