C₃₃H₅₀N₄O₁₃

Base Information

• Chemical Name: C₃₃H₅₀N₄O₁₃
• CAS No.: 926912-96-1
• Molecular Formula: C₃₃H₅₀N₄O₁₃
• Molecular Weight: 710.779
• Mol file: 926912-96-1.mol

Synonyms:C₃₃H₅₀N₄O₁₃

Chemical Property of C₃₃H₅₀N₄O₁₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₅₀N₄O₁₃

There total 5 articles about C₃₃H₅₀N₄O₁₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

3,4-bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxymethyl}-1H-pyrrole-2,5-dicarboxylic acid monobenzyl ester (926912-94-9) + tert-butyl carbamimidoylcarbamate (219511-71-4) → C33H50N4O13 (926912-96-1)

Guidance literature:

With dmap; 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 3h;

DOI:10.1002/chem.200600573

Reference yield:

3,4-bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxymethyl}-1H-pyrrole-2,5-dicarboxylic acid 2-benzyl ester 5-tert-butyl ester (926913-32-8) → C33H50N4O13 (926912-96-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 40 percent / TFA / CH₂Cl₂ / -20 - 5 °C

2: 45 percent / HCTU; DMAP / CH₂Cl₂; dimethylformamide / 3 h / 20 °C

With dmap; 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/chem.200600573

Reference yield:

3,4-bis-bromomethyl-1H-pyrrole 2,5-dicarboxylic acid 2-tert-butyl ester 5-ethyl ester (492454-08-7) → C33H50N4O13 (926912-96-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 64 percent / NEt₃ / CH₂Cl₂ / 24 h / 100 °C

2: 70 percent / sodium / 3 h / 0.9 Torr / Heating

3: 40 percent / TFA / CH₂Cl₂ / -20 - 5 °C

4: 45 percent / HCTU; DMAP / CH₂Cl₂; dimethylformamide / 3 h / 20 °C

With dmap; 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); sodium; triethylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/chem.200600573

upstream raw materials:

3,4-bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxymethyl}-1H-pyrrole-2,5-dicarboxylic acid monobenzyl ester

tert-butyl carbamimidoylcarbamate

3,4-bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxymethyl}-1H-pyrrole-2,5-dicarboxylic acid 2-benzyl ester 5-tert-butyl ester

3,4-bis-bromomethyl-1H-pyrrole 2,5-dicarboxylic acid 2-tert-butyl ester 5-ethyl ester

Downstream raw materials:

C₄₅H₇₈N₄O₁₃Si₂