ETHYL 2,2'-BIS(ETHOXYCARBONYL)-3-PHENYLPROPANOATE

Base Information

• Chemical Name: ETHYL 2,2'-BIS(ETHOXYCARBONYL)-3-PHENYLPROPANOATE
• CAS No.: 16515-84-7
• Molecular Formula: C17H22 O6
• Molecular Weight: 322.35
• Hs Code.: 2917399090
• Mol file: 16515-84-7.mol

Synonyms:1,1,1-Ethanetricarboxylicacid, 2-phenyl-, triethyl ester (8CI,9CI); Diethyl 2-benzyl-2-(ethoxycarbonyl)malonate

Chemical Property of ETHYL 2,2'-BIS(ETHOXYCARBONYL)-3-PHENYLPROPANOATE

Chemical Property:

• Boiling Point: 423.7oC at 760 mmHg
• Flash Point: 183.2oC
• PSA: 78.90000
• Density: 1.129g/cm3
• LogP: 2.14820
• Solubility.: Chloroform

Purity/Quality:

95% ^*data from raw suppliers

Ethyl2,2’-Bis(ethoxycarbonyl)-3-phenylpropanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Ethyl 2,2’-Bis(ethoxycarbonyl)-3-phenylpropanoate (cas# 16515-84-7) is a compound useful in organic synthesis.

Technology Process of ETHYL 2,2'-BIS(ETHOXYCARBONYL)-3-PHENYLPROPANOATE

There total 3 articles about ETHYL 2,2'-BIS(ETHOXYCARBONYL)-3-PHENYLPROPANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

methanetricarboxylic acid triethyl ester (6279-86-3) + benzyl alcohol (100-51-6,185532-71-2) → 1,1,1-tris(ethoxycarbonyl)-2-phenylethane (16515-84-7)

Guidance literature:

With thiamine diphosphate; diethylazodicarboxylate; In diethyl ether; Ambient temperature;

DOI:10.1016/0040-4020(96)00781-8

Reference yield:

sodium 1,3-diethoxy-2-(ethoxycarbonyl)-1,3-dioxopropan-2-ide (68922-87-2) + benzyl chloride (100-44-7) → 1,1,1-tris(ethoxycarbonyl)-2-phenylethane (16515-84-7)

Guidance literature:

In N,N-dimethyl-formamide; toluene; at 90 ℃; for 20h;

Reference yield:

methanetricarboxylic acid triethyl ester (6279-86-3) + benzyl chloride (100-44-7) → 1,1,1-tris(ethoxycarbonyl)-2-phenylethane (16515-84-7)

Guidance literature:

Multistep reaction; (i) Na, acetone, (ii) /BRN= 471308/;

upstream raw materials:

methanetricarboxylic acid triethyl ester

benzyl chloride

benzyl alcohol

sodium 1,3-diethoxy-2-(ethoxycarbonyl)-1,3-dioxopropan-2-ide

Refernces

• 1、 -. "NOVEL 3, 4-PROPYLENEDIOXYTHIOPHENE DERIVATIVES WITH PENDANT FUNCTIONAL GROUPS". Page/Page column 6-7. . Retrieved 2010/11/24.