4-(1-Naphthylvinyl)pyridine

Base Information

• Chemical Name: 4-(1-Naphthylvinyl)pyridine
• CAS No.: 16375-56-7
• Molecular Formula: C17H13 N
• Molecular Weight: 231.29
• Hs Code.: 2933399090
• European Community (EC) Number: 678-280-4
• UNII: XB7DL3H8SX
• Nikkaji Number: J847.760D,J208.795B
• Wikipedia: Naphthylvinylpyridine
• Wikidata: Q10859530
• ChEMBL ID: CHEMBL353384
• Mol file: 16375-56-7.mol

Synonyms:Naphthylvinylpyridine

Chemical Property of 4-(1-Naphthylvinyl)pyridine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 82°C
• Refractive Index: 1.648
• Boiling Point: 409.3°Cat760mmHg
• PKA: 5.44±0.10(Predicted)
• Flash Point: 182.7°C
• PSA: 12.89000
• Density: 1.156g/cm³
• LogP: 4.40520
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Chloroform (Slightly), DMSO (Slightly)
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 231.104799419
• Heavy Atom Count: 18
• Complexity: 277

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(1-Naphthylvinyl)pyridine ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2C=CC3=CC=NC=C3
• Isomeric SMILES: C1=CC=C2C(=C1)C=CC=C2/C=C/C3=CC=NC=C3

Technology Process of 4-(1-Naphthylvinyl)pyridine

There total 7 articles about 4-(1-Naphthylvinyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

picoline (108-89-4) + 1-naphthaldehyde (66-77-3) → 4-[2-(1-naphtalenyl)ethenyl]-pyridine (16375-56-7)

Guidance literature:

With acetic anhydride; sodium hydroxide; for 4h; Reflux;

DOI:10.1002/anie.202011989

Reference yield:

1-(1-naphthyl)-2-pyridin-4-ylethanol → 4-[2-(1-naphtalenyl)ethenyl]-pyridine (16375-56-7)

Guidance literature:

With pyridine; trichlorophosphate; at 5 - 20 ℃; for 3h;

DOI:10.1016/S0009-2614(01)01366-5

Reference yield:

picoline (108-89-4) → 4-[2-(1-naphtalenyl)ethenyl]-pyridine (16375-56-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: LDA / tetrahydrofuran; hexane / 1 h / 5 °C

1.2: tetrahydrofuran; hexane / 20 °C

2.1: pyridine; POCl₃ / 3 h / 5 - 20 °C

With pyridine; lithium diisopropyl amide; trichlorophosphate; In tetrahydrofuran; hexane;

DOI:10.1016/S0009-2614(01)01366-5

upstream raw materials:

trans-1-(1-Naphthyl)-2-(4'-pyridyl)ethylene

picoline

1-naphthaldehyde

pyridine-4-carbaldehyde

Downstream raw materials:

1-(1-naphthyl)-2-(4-pyridyl)ethane

Refernces

• 1、 Dutta, Basudeb,Dey, Arka,Sinha, Chittaranjan,Ray, Partha Pratim,Mir, Mohammad Hedayetullah. "Photochemical Structural Transformation of a Linear 1D Coordination Polymer Impacts the Electrical Conductivity". . p. 8029 - 8032. Retrieved 2018.
• 2、 Nguyen, Thanh Binh,Nguyen, Tuan Minh,Retailleau, Pascal. "[2+2] Photodimerization of Stilbazoles Promoted by Oxalic Acid in Suspension". supporting information. p. 4682 - 4689. Retrieved 2020/04/15.