9α-bromo-16β-methyl-11β,12β,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 17,20-dipropionate 12-benzoate

Base Information

Chemical Name:9α-bromo-16β-methyl-11β,12β,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 17,20-dipropionate 12-benzoate
CAS No.:127034-67-7
Molecular Formula:C₃₅H₄₁BrO₉
Molecular Weight:685.609
Hs Code.:

Synonyms:9α-bromo-16β-methyl-11β,12β,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 17,20-dipropionate 12-benzoate

Suppliers and Price of 9α-bromo-16β-methyl-11β,12β,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 17,20-dipropionate 12-benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 9α-bromo-16β-methyl-11β,12β,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 17,20-dipropionate 12-benzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 9α-bromo-16β-methyl-11β,12β,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 17,20-dipropionate 12-benzoate

There total 2 articles about 9α-bromo-16β-methyl-11β,12β,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 17,20-dipropionate 12-benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 127034-62-2
9α-bromo-16β-methyl-11β,12β,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 17,21-dipropionate

: 98-88-4
benzoyl chloride

: 127034-67-7
9α-bromo-16β-methyl-11β,12β,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 17,20-dipropionate 12-benzoate

Guidance literature:: With pyridine; dmap; In dichloromethane; at 23 ℃; for 5h;
DOI:10.1021/jm00169a004

Reference yield:

: 127034-57-5
16β-methyl-12β,17α,21-trihydroxypregna-1,2,9(11)-triene-3,20-dione 17,21-dipropionate

: 127034-67-7
9α-bromo-16β-methyl-11β,12β,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 17,20-dipropionate 12-benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / N-bromoacetamide, 0.5 N HClO₄ / dioxane / 22 h / 23 °C

2: 86 percent / pyridine, 4-(N,N-dimethylamino)pyridine (DMAP) / CH₂Cl₂ / 5 h / 23 °C

With pyridine; dmap; perchloric acid; N-bromoacetamide; In 1,4-dioxane; dichloromethane;
DOI:10.1021/jm00169a004