C₁₄H₁₇NO₅

Base Information

• Chemical Name: C₁₄H₁₇NO₅
• CAS No.: 946428-57-5
• Molecular Formula: C₁₄H₁₇NO₅
• Molecular Weight: 279.293
• Mol file: 946428-57-5.mol

Synonyms:C₁₄H₁₇NO₅

Chemical Property of C₁₄H₁₇NO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₇NO₅

There total 9 articles about C₁₄H₁₇NO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

C16H19NO7 (946428-56-4) → C14H17NO5 (946428-57-5)

Guidance literature:

With hydrogenchloride; for 40h; Heating;

DOI:10.1021/ol070980t

Reference yield:

N-carbomethoxy-L-3-dehydroproline methyl ester → C14H17NO5 (946428-57-5)

Guidance literature:

Multi-step reaction with 7 steps

1.1: aq. AcOH / Pd(OAc)2 / acetonitrile / 4 h / 60 °C

1.2: 65 percent / 2,4-lutidine; trifluoroacetic anhydride / toluene

2.1: NaH / tetrahydrofuran / 0 - 20 °C

2.2: 79 percent / tetrahydrofuran

3.1: LiHMDS / tetrahydrofuran / 0.5 h / 0 °C

3.2: 72 percent / tetrahydrofuran / 18 h / 0 - 20 °C

4.1: H₂O₂ / tetrahydrofuran / 0 - 20 °C

5.1: H₂ / PtO₂ / ethanol / 3620.13 Torr

6.1: 80 percent / aq. HCl / 12 h / 80 °C

7.1: 75 percent / aq. HCl / 40 h / Heating

With hydrogenchloride; hydrogen; dihydrogen peroxide; sodium hydride; acetic acid; lithium hexamethyldisilazane; platinum(IV) oxide; palladium diacetate; In tetrahydrofuran; ethanol; acetonitrile; 2.2: Michael reaction;

DOI:10.1021/ol070980t

Reference yield:

2-methoxyphenyldiazonium tetrafluoroborate (492-95-5) → C14H17NO5 (946428-57-5)

Guidance literature:

Multi-step reaction with 7 steps

1.1: aq. AcOH / Pd(OAc)2 / acetonitrile / 4 h / 60 °C

1.2: 65 percent / 2,4-lutidine; trifluoroacetic anhydride / toluene

2.1: NaH / tetrahydrofuran / 0 - 20 °C

2.2: 79 percent / tetrahydrofuran

3.1: LiHMDS / tetrahydrofuran / 0.5 h / 0 °C

3.2: 72 percent / tetrahydrofuran / 18 h / 0 - 20 °C

4.1: H₂O₂ / tetrahydrofuran / 0 - 20 °C

5.1: H₂ / PtO₂ / ethanol / 3620.13 Torr

6.1: 80 percent / aq. HCl / 12 h / 80 °C

7.1: 75 percent / aq. HCl / 40 h / Heating

With hydrogenchloride; hydrogen; dihydrogen peroxide; sodium hydride; acetic acid; lithium hexamethyldisilazane; platinum(IV) oxide; palladium diacetate; In tetrahydrofuran; ethanol; acetonitrile; 2.2: Michael reaction;

DOI:10.1021/ol070980t

upstream raw materials:

C₁₆H₁₉NO₇

C₁₆H₂₁NO₆

4-(o-methoxyphenyl)dehydroproline

C₂₂H₂₉NO₉

Downstream raw materials:

C₂₄H₂₇NO₇