2-AMINOHEX-5-ENOIC ACID

Base Information

• Chemical Name: 2-AMINOHEX-5-ENOIC ACID
• CAS No.: 16258-05-2
• Molecular Formula: C6H11 N O2
• Molecular Weight: 129.16
• Hs Code.: 2922499990
• Mol file: 16258-05-2.mol

Synonyms:Homoallylglycine

Chemical Property of 2-AMINOHEX-5-ENOIC ACID

Chemical Property:

• Boiling Point: 242.0±28.0 °C(Predicted)
• PKA: 2.31±0.10(Predicted)
• PSA: 63.32000
• Density: 1.064±0.06 g/cm3(Predicted)
• LogP: 1.06480
• Storage Temp.: Amber Vial, Refrigerator, Under inert atmosphere
• Solubility.: Methanol (Slightly, Heated), Water (Slightly, Heated)

Purity/Quality:

98%min ^*data from raw suppliers

Homoallylglycine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Homoallylglycine is a glycine derivative that displays translational activity in Escherichia coli.

Technology Process of 2-AMINOHEX-5-ENOIC ACID

There total 5 articles about 2-AMINOHEX-5-ENOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Nε-(Methoxycarbonyl)-Nε-nitroso-L-lysine (90957-39-4) → rac-6-hydroxynorleucine (5462-80-6) + D,L-2-amino-5-hexenoic acid (16258-05-2) + cyclohexyl-carbamic acid methyl ester (5817-68-5)

Guidance literature:

With phosphate buffer; cyclohexylamine; In water; at 37 ℃; for 0.5h; Yield given. Yields of byproduct given;

DOI:10.1007/BF00758997

Reference yield:

Nε-(2-Chloroethoxycarbonyl)-Nε-nitroso-L-lysine (90957-40-7) → rac-6-hydroxynorleucine (5462-80-6) + 2-chloroethyl N-cyclohexylcarbamate (31502-57-5) + D,L-2-amino-5-hexenoic acid (16258-05-2)

Guidance literature:

With phosphate buffer; cyclohexylamine; In water;

DOI:10.1007/BF00758997

Reference yield:

cyclohexylamine (108-91-8,157973-60-9) + Nε-(2-Chloroethoxycarbonyl)-Nε-nitroso-L-lysine (90957-40-7) → rac-6-hydroxynorleucine (5462-80-6) + 2-chloroethyl N-cyclohexylcarbamate (31502-57-5) + D,L-2-amino-5-hexenoic acid (16258-05-2)

Guidance literature:

With phosphate buffer; In water; at 37 ℃;

DOI:10.1007/BF00758997

upstream raw materials:

cyclohexylamine

N^ε-(Methoxycarbonyl)-N^ε-nitroso-L-lysine

N^ε-(2-Chloroethoxycarbonyl)-N^ε-nitroso-L-lysine

Downstream raw materials:

Fmoc-L-Asn(Trt)-DL-Hag-OH

(R)-2-(Acryloyl-benzyl-amino)-hex-5-enoic acid methyl ester

(R)-2-[Allyl-(4-methoxy-benzyl)-amino]-hex-5-enoic acid methyl ester

(2R)-2-amino-5-hexenoic acid

Refernces

• 1、 Gopko, V. F.,Anoshina, G. M.,Radina, L. B.. "SYNTHESIS AND ANTITUMORIGENIC ACTIVITY OF L-LYSINE NITROSOCARBAMATES". . p. 165 - 168. Retrieved 2007/10/02.