(2R,6R,10R)-2-(4-methoxy-2,3,5-trimethylphenoxy)-2,6,10,14-tetramethylpentadecanoic acid methyl ester

Base Information

• Chemical Name: (2R,6R,10R)-2-(4-methoxy-2,3,5-trimethylphenoxy)-2,6,10,14-tetramethylpentadecanoic acid methyl ester
• CAS No.: 1215112-51-8
• Molecular Formula: C₃₀H₅₂O₄
• Molecular Weight: 476.74

Synonyms:(2R,6R,10R)-2-(4-methoxy-2,3,5-trimethylphenoxy)-2,6,10,14-tetramethylpentadecanoic acid methyl ester

Chemical Property of (2R,6R,10R)-2-(4-methoxy-2,3,5-trimethylphenoxy)-2,6,10,14-tetramethylpentadecanoic acid methyl ester

Chemical Property:

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Technology Process of (2R,6R,10R)-2-(4-methoxy-2,3,5-trimethylphenoxy)-2,6,10,14-tetramethylpentadecanoic acid methyl ester

There total 1 articles about (2R,6R,10R)-2-(4-methoxy-2,3,5-trimethylphenoxy)-2,6,10,14-tetramethylpentadecanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

(2S,6R,10R)-2-hydroxy-2,6,10,14-tetramethylpentadecanoic acid methyl ester (1215112-49-4) + 4-methoxy-2,3,5-trimethylphenol (130422-86-5) → (2R,6R,10R)-2-(4-methoxy-2,3,5-trimethylphenoxy)-2,6,10,14-tetramethylpentadecanoic acid methyl ester (1215112-51-8)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In toluene; at 100 ℃; for 4h; optical yield given as %de; Mitsunobu reaction;

DOI:10.1002/chem.200902754

Reference yield: 100.0%

(2R,6R,10R)-2-(4-methoxy-2,3,5-trimethylphenoxy)-2,6,10,14-tetramethylpentadecanoic acid methyl ester (1215112-51-8) → (2R,6R,10R)-2-(4-methoxy-2,3,5-trimethylphenoxy)-2,6,10,14-tetramethyl-1-pentadecanol (1215112-54-1)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 0.416667h;

DOI:10.1002/chem.200902754

upstream raw materials:

(2S,6R,10R)-2-hydroxy-2,6,10,14-tetramethylpentadecanoic acid methyl ester

4-methoxy-2,3,5-trimethylphenol

Downstream raw materials:

(2R,6R,10R)-2-(4-methoxy-2,3,5-trimethylphenoxy)-2,6,10,14-tetramethyl-1-pentadecanol

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