1-(2-methoxyphenyl)-4-<<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>phenyl>sulfonyl>piperazine

Base Information

Chemical Name:1-(2-methoxyphenyl)-4-<<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>phenyl>sulfonyl>piperazine
CAS No.:71422-38-3
Molecular Formula:C₂₇H₂₅F₃N₄O₃S
Molecular Weight:542.582
Hs Code.:

Synonyms:1-(2-methoxyphenyl)-4-<<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>phenyl>sulfonyl>piperazine

Suppliers and Price of 1-(2-methoxyphenyl)-4-<<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>phenyl>sulfonyl>piperazine

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Chemical Property of 1-(2-methoxyphenyl)-4-<<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>phenyl>sulfonyl>piperazine

Chemical Property:

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Technology Process of 1-(2-methoxyphenyl)-4-<<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>phenyl>sulfonyl>piperazine

There total 5 articles about 1-(2-methoxyphenyl)-4-<<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>phenyl>sulfonyl>piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35386-24-4
1-(2-Methoxyphenyl)piperazine

: 71422-38-3
1-(2-methoxyphenyl)-4-<<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>phenyl>sulfonyl>piperazine

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / CH₂Cl₂ / 17 h

2: H₂ / PtO₂ / CHCl₃

3: 1.) acetyl chloride / 1.) ethanol, 10 min, 2.) ethanol, a) reflux, 3 h, b) RT, overnight

With hydrogen; triethylamine; acetyl chloride; platinum(IV) oxide; In dichloromethane; chloroform;
DOI:10.1021/jm00151a021

Reference yield:

: 71422-91-8
1-<(4-nitrophenyl)sulfonyl>-4-(2-methoxyphenyl)piperazine

: 71422-38-3
1-(2-methoxyphenyl)-4-<<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>phenyl>sulfonyl>piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / PtO₂ / CHCl₃

2: 1.) acetyl chloride / 1.) ethanol, 10 min, 2.) ethanol, a) reflux, 3 h, b) RT, overnight

With hydrogen; acetyl chloride; platinum(IV) oxide; In chloroform;
DOI:10.1021/jm00151a021

Reference yield:

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 71422-38-3
1-(2-methoxyphenyl)-4-<<4-<<7-(trifluoromethyl)-4-quinolinyl>amino>phenyl>sulfonyl>piperazine

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / CH₂Cl₂ / 17 h

2: H₂ / PtO₂ / CHCl₃

3: 1.) acetyl chloride / 1.) ethanol, 10 min, 2.) ethanol, a) reflux, 3 h, b) RT, overnight

With hydrogen; triethylamine; acetyl chloride; platinum(IV) oxide; In dichloromethane; chloroform;
DOI:10.1021/jm00151a021